Abstract: Resveratrol is a natural non-flavonoid polyphenol compound with many pharmacological activities such as anti-inflammatory, anti-free radical, anti-cardiovascular and anti-tumor activities. However, due to its poor water solubility and easy decomposition under light, the bioavailability of resveratrol is low, which limits its application in foods and medicines. The nanodelivery system is a new delivery system with great development potential due to its many advantages such as good biocompatibility, targeting and slow release. Intensive research has been made on resveratrol nanodelivery systems in recent years. Hence, this article reviews the main pharmacological effects and pharmacokinetic properties of resveratrol as well as recent progress in resveratrol nanodelivery systems. Through this review, we hope to provide a reference for the future research and application of resveratrol.

Key words: resveratrol; pharmacological effects; pharmacokinetics; bioavailability; nanodelivery systems