FOOD SCIENCE ›› 2022, Vol. 43 ›› Issue (23): 346-355.doi: 10.7506/spkx1002-6630-20211228-317

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Progress in Research on the Effect of Diet Structure and Nutritional Composition on Depression

XU Huihui, CHEN Xu, ZHAO Fang, MAO Ruoxi, WANG Wenli, CHENG Zhimei, ZHANG Yali   

  1. (College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China)
  • Online:2022-12-15 Published:2022-12-28

Abstract: Depression is becoming the second biggest killer of mankind after cancer, with an estimated 340 million people worldwide suffering from this disease. Research reports have shown that diet affects depression. This paper reviews the effects of different dietary structures such as high protein diet, vegetarian diet, high-fat diet and ketogenic diet on depression, discusses the effect of nutritional components such as folic acid, dietary fiber, polyphenolic compounds, vitamins and polyunsaturated fatty acids in improving depression, and summarizes the three mechanisms by which dietary structures and nutritional components affect depression: by regulating the metabolism of monoamine neurotransmitters, the digestive tract and the intestinal flora, and neuroendocrine system. This article will provide new inspirations to prevent and interfere in depression through diet.

Key words: depression; monoamine neurotransmitters; vegetarianism; dietary fiber; intestinal flora

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