Research Progress of Screening Methods for Hypolipidemic Components in vitro

doi:10.7506/spkx1002-6630-201013066

FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (13): 287-291.doi: 10.7506/spkx1002-6630-201013066

• Analysis & Detection • Previous Articles Next Articles

Research Progress of Screening Methods for Hypolipidemic Components in vitro

CHEN Ji-cheng，LU Xiao-feng，HE Guo-qing*

School of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310029, China

Received:2010-01-05 Revised:2010-05-10 Online:2010-07-01 Published:2010-12-29
Contact: HE Guo-qing* E-mail:gqhe@zju.edu.cn

Abstract

Abstract:

Abnormal lipid metabolism is one of risk factors for atherosclerotic cardiovascular disease. The commonly used hypolipidemic drugs have toxicity to some extents. Screening effective, non-toxic, natural hypolipidemic ingredients has become one of hot topics in the fields of modern medicine, nutrition and biotechnology at home and abroad. Animal models with hyperlipidemia were high cost, time-consuming and unsuitable for high throughput screening. A convenient strategy for developing hypolipidemic drugs and health foods is to screen bioactive components in vitro. In this paper, screening methods for hypolipidemic drugs in vitro have been reviewed, which will provide references for further research of hypolipidemic components.

Key words: hyperlipemia, cholesterol, hypolipidemic, screening methods in vitro

CLC Number:

TS201.4

CHEN Ji-cheng，LU Xiao-feng，HE Guo-qing*. Research Progress of Screening Methods for Hypolipidemic Components in vitro[J]. FOOD SCIENCE, 2010, 31(13): 287-291 https://doi.org/10.7506/spkx1002-6630-201013066

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Research Progress of Screening Methods for Hypolipidemic Components in vitro

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