FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (11): 77-80.doi: 10.7506/spkx1002-6630-201011017

• Basic Research • Previous Articles     Next Articles

Synthesis of O-Carboxymethyl Chitosan and Its Effect on the Growth of Aspergillus niger

LI Xiao-fang FENG Xiao-qiang YANG Sheng*   

  1. College of Life Science and Chemistry, Tianshui Normal University, Tianshui 741001, China
  • Received:2009-09-18 Revised:2010-03-02 Online:2010-06-01 Published:2010-12-29
  • Contact: YANG Sheng E-mail:lix_f06@lzu.cn

Abstract:

O-carboxymethyl chitosan (OCMC) was prepared and characterized by IR spectroscopy. The effect of OCMC on the growth of Aspergillus niger was also investigated. Results indicated that an obvious inhibitory effect of OCMC on the growth of Aspergillus niger was observed after 1 day of cultivation on agar plates with the addition of OCMC. OCMC at the concentration of 1.0 mg/mL exhibited the strongest inhibitory effect. The interaction between chitosan or OCMC and ct-DNA  could result in the structural damage of ct-DNA.

Key words: O-carboxymethyl chitosan, Aspergillus niger, inhibitory activity, DNA

CLC Number: