Screening and Hypocholesterolemic Effect of Lactobacillus fermentum

doi:10.7506/spkx1002-6630-201009050

FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (9): 224-228.doi: 10.7506/spkx1002-6630-201009050

• Nutrition & Hygiene • Previous Articles Next Articles

Screening and Hypocholesterolemic Effect of Lactobacillus fermentum

YAN Yu-ting1，PAN Dao-dong1,2,*

1. Branch Center of National Dairy Products Processing Technology Development, Nanjing Normal University, Nanjing 210097,
China；2. Faculty of Life Science and Biotechnology, Ningbo University, Ningbo 315211, China

Received:2009-09-07 Online:2010-05-01 Published:2010-12-29
Contact: PAN Dao-dong E-mail:daodongpan@163.com

Abstract

Abstract:

The strain SM-7 with hpocholesterolemic activity was screened from 10 lactic acid bacteria (LAB) strains isolated from koumiss in Xinjiang and its hpocholesterolemic effect in mice was investigated. The SM-7 was identified as Lactobacillus fermentum and could reduce 66.82% of cholesterol in the medium. The effect of strain SM-7 on serum TC, TG, HDL-C, LDLC, body weight, liver and kidney were investigated in ICR mice with hyperlipemia. Results showed serum TC, TG and LDL-C concentrations were exhibited a significant decrease (P < 0.01) while no obvious change was observed in serum HDL-C concentration (P > 0.05). These investigations suggested that Lactobacillus fermentum SM-7 strain had a significant effect on cholesterol-reducing function in mice with hyperlipemia.

Key words: Lactobacillus fermentum, screening, cholesterol-reducing, mechanism

CLC Number:

Q939.117

YAN Yu-ting1，PAN Dao-dong1,2,*. Screening and Hypocholesterolemic Effect of Lactobacillus fermentum[J]. FOOD SCIENCE, 2010, 31(9): 224-228.

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Screening and Hypocholesterolemic Effect of Lactobacillus fermentum

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