食品科学

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红肉、N-羟乙酰神经氨酸与癌症关系的研究进展

范杏丹,李红卫   

  1. 厦门大学公共卫生学院,福建 厦门 361102
  • 出版日期:2014-08-15 发布日期:2014-08-25

Progress in Studies on Relationship between Red Meat Intake, N-Glycolylneuraminic Acid and Cancer Risk

FAN Xing-dan, LI Hong-wei   

  1. School of Public Health, Xiamen University, Xiamen 361102, China
  • Online:2014-08-15 Published:2014-08-25

摘要:

世界癌症研究基金会报告指出,过多摄入红肉会增加患癌症的风险,红肉可能是导致某些癌症的原因之一。有研究得出,摄入红肉后身体内产生的一种唾液酸——N-羟乙酰神经氨酸(N-glycolylneuraminic acid,Neu5Gc)可能与癌症的发生有关。本文从红肉与癌的关系,引出对Neu5Gc的讨论,从它的结构、来源、生理功能到临床应用价值,最后是与癌症可能的机制讨论,并重申它的研究价值。

关键词: 红肉, N-羟乙酰神经氨酸, 唾液酸, 癌症

Abstract:

According to the World Cancer Research Fund, excessive intake of red meat may increase the risk of cancer and
be one of the causes of some tumors. Studies have concluded that N-glycolylneuraminic acid (Neu5Gc), a kind of sialic acid
produced in the human body after eating red meat, may be associated with the occurrence of cancer. Starting with addressing
the relationship between red meat and cancer, this paper discusses the structure, source, physiological function and clinical
application value of Neu5Gc. At the end of the paper, the possible carcinogenic mechanism of Neu5Gc as well as its research
value is explored.

Key words: red meat, N-glycolylneuraminic acid, sialic acid, cancer

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