关键词: 牦牛骨营养粉, 大鼠试验, 骨密度, 血清生化指标, 电解质

Abstract:

Objective: To investigate effects of the mixture of ultrafine yak bone powder, casein phosphopeptide (CPP) and inulin on rat bone density and serum biochemical indexes. Method: Fifty Wistar female rats with about 90 ± 10 g body weight were divided into 5 groups at random, namely control group (normal diet), experiment group NO.1 (fed the diet containing 50% ultrafine yak bone powder plus 10% CPP plus 40% inulin), experiment group NO.2 (fed the diet containing 50% ultrafine yak bone powder plus 20% CPP plus 30% inulin), experiment NO.3 (fed the diet containing 50% ultrafine yak bone powder plus 30% CPP plus 20% inulin), and experiment group (fed the diet containing 50% ultrafine yak bone powder plus 40% CPP plus 10% inulin). All the diets for the five groups contain 10±1 g calcium /kg. Results: Compared to the control group, the bone densities of four experiment groups rise by 23.48%, 20.0%, 21.74% and 18.26%, respectively. There are no statistical differences (p＞0.05) in contents of AKP and TG, the CHO content of experiment group NO.2 is significantly lower 9.82% than that of the control group (p＜0.05), and there are no statistical differences (p＞0.05) in contents of K+ and Na+ in serum as well, but compared to the control group the Ca+ contents of four experiment groups decline by 47.1%, 12%, 14.49% and 8.29%, respectively. The serum Cl－ content of experiment group NO.2 is significantly lower than that of the control group and other three experiment groups (p＜0.05). Conclusion: Nutritious yak bone powder may improve bone density and there are no adverse effects on the serum biochemical indexes.

Key words: nutritious yak bone powder, rat experiment, bone density, serum biochemical index, serum electrolyte