食品科学 ›› 1999, Vol. 20 ›› Issue (6): 54-56.

• 营养卫生 • 上一篇    下一篇

松籽油对大鼠血脂及脂质过氧化的影响

 蔡秀成,  王力光,  邢立新, 郭英,  马文君   

  1. 吉林省卫生防疫站; 白求恩医科大学预防医学院; 广东省人民医院营养科
  • 出版日期:1999-06-15 发布日期:2011-12-09

 CAI  Xiu-Cheng,   Wang-Li-Guang,   Xing-Li-Xin, GUO  Ying,   Ma-Wen-Jun   

  • Online:1999-06-15 Published:2011-12-09

摘要: 观察在高脂血症形成过程中松籽油对大鼠血脂和脂质过氧化的影响。在高脂饲料中加入6%的松籽油喂饲Wistar雄性大鼠三周,使高脂血症大鼠血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)的含量、LDL-C与高密度脂蛋白胆固醇(UDL-C)比值(LDL-C/HDL-C)、致动脉粥样硬化指数(AI)的升高作用和HDL-C/TC比值的降低程度得到减轻。高脂摄入使大鼠肝组织中谷胱甘肽过氧化物酶(GSH-PX)活性降低而过氧化脂质(LPO)含量增加,但松籽油组大鼠肝脏LPO水平低于月见草油组。提示松籽油有利于调节血脂及预防动脉粥样硬化(AS)。

关键词: 松籽油, 血脂, 脂质过氧化

Abstract:  This study was conducted to investigate the effect of pine-seed oil on serum lipid and lipid peroxidationto experimental hyperlipidemia in rats.Male adult wistar rats were fed on the test diet containing 94% hyperlipid dietand 6%pine-seed oil for 3 weeks.The result showed that the value of trilyceride(TG).total cholesterol (TC),lowdensity lipoprotein-cholesterol (LDL-C).LDL-C/high density lipoprotein-cholesterol (HDL-C) ratio,atherogenicindex (AI) increased and the value of HDL-C/TC ratio decreased in the group with pine-seed oil supplemenation wereless than that the model control group with lard supplemenation.Compared with the normal group.the glutathion perosidase (GSH-PX) activity was lower and lipid peroxide (LPO)level was higher in liver of rats feeding lipid-rich food .But LPO level in pine-seed oil group was lower than that ofevening primrose seed oil group.These results suggested that utilzation of pine-seed oil to regulate serum lipid andprevent atherosclerosis.

Key words:  , Pine-seed oil Serum lipid Lipid peroxidation;