食品科学

• 生物工程 • 上一篇    下一篇

免疫初乳与双歧杆菌复合微胶囊壁材的筛选

杨 柳,张英楠,尤丽新,陈海燕,马井喜   

  1. 长春科技学院生物食品学院,吉林 长春 130600
  • 出版日期:2014-04-15 发布日期:2014-04-18

Screening of Capsule Wall for Complex Microcapsules of Immune Colostrum and Bifidobacteria

YANG Liu, ZHANG Ying-nan*, YOU Li-xin, CHEN Hai-yan, MA Jing-xi   

  1. College of Organism and Food, Changchun University of Science and Technology, Changchun 130600, China
  • Online:2014-04-15 Published:2014-04-18

摘要:

以双歧杆菌发酵免疫初乳,采用真空冷冻干燥技术研制成冻干粉,并以冻干粉为芯材、以不同肠溶材料作为壁材,采用空气悬浮微胶囊化的方法制成免疫与微生态双活性肠溶制剂。从不同壁材的成膜性、喷雾性、溶出度、肠溶性、耐酸性、贮存稳定性等方面确定以欧巴代作为微胶囊的壁材,从喷雾性能及微胶囊的性能考虑,包衣液的质量分数为15%,芯材、壁材质量比为10∶3。

关键词: 双歧杆菌, 免疫球蛋白, 微胶囊, 壁材

Abstract:

Gastro-resistant complex microcapsules were prepared with freeze-dried powder of immune colostrum fermentedwith Bifidobacterium adolescentis as core material by air suspension technique. Opadry was determined as the optimal wallmaterial based on film-forming property, spraying capacity, dissolution rate, enteric solubility, acid resistance and storagestability. The optimal coating concentration and mass ratio of core to wall material were 15% and 10:3, respectively, whenspraying capacity and microcapsule performance were taken into account.

Key words: Bifidobacterium adolescentis, IgG, microcapsule, capsule wall