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Genetic Differences and Gastric Protective Effect of Morchella Strains

WEI Wei, YU Meng-yao, XU Xiao-yan, JIANG Nan, YE Li-ming, LUO Xia   

  1. 1. Celluar and Molecular Laboratory of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences,
    Chengdu 610041, China; 2. West China School of Pharmacy, Sichuan University, Chengdu 610041, China
  • Online:2014-04-15 Published:2014-04-18

Abstract:

In this study, inter-simple sequence repeats (ISSR) molecular labeling technology was used to explore the geneticdiversity of Morchella strains on the basis of mycelium biomass in submerged culture, and their gastric protective effects onethanol-induced acute gastric mucosal injury model in mice were compared. Results showed that 16 Morchella strains weredivided into two groups. The biomass of M1-M10 was higher than that of other strains, and the gastric protective effect ofM1, M2 and M3 was better than that of other strains. Mycelium biomasses and gastric protective effects varied in differentMorchella strains.

Key words: Morchella, inter-simple sequence repeats (ISSR), biomass, gastric protective effects