关键词: 纳他霉素, 培养基, 融合子, 响应面分析

Abstract:

In this study, on the basis of shaking culture medium of fusant Sr-1 and single-factor test results of fermentation conditions, the optimum fermentation medium compositions and conditions of fusant Sr-1 for natamycin production were obtained by means of response surface methodology, which were as follows: glucose 33 g/L, dextrin 7.7 g/L, tryptone 26 g/L, yeast extract powder 8.2 g/L，initial pH 7.0, cell age of fermentation strain 28 h and fermentation time 72 h.

Key words: natamycin, culture medium, fusant, response surface methodology