食品科学 ›› 2011, Vol. 32 ›› Issue (1 ): 256-259.doi: 10.7506/spkx1002-6630-201101061

• 专题论述 • 上一篇    下一篇

蛋白质组学在反式脂肪酸和心血管疾病关系研究中的进展

于化泓,李湘梅,刘蓉   

  1. 南昌大学 食品科学与技术国家重点实验
  • 收稿日期:2010-09-21 出版日期:2011-01-15 发布日期:2010-12-28
  • 通讯作者: 于化泓 E-mail:yhh917@163.com
  • 基金资助:

    江西省教育厅青年科学基金项目(2008GQY0023)

Research Progress of Protemics Applied to Clarify the Relationship between Cardiovascular Diseases and Trans-fatty Acids

YU Hua-hong,LI Xiang-mei,LIU Rong   

  1. State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China
  • Received:2010-09-21 Online:2011-01-15 Published:2010-12-28
  • Contact: YU Hua-hong E-mail:yhh917@163.com

摘要:

近年来,众多研究发现反式脂肪酸对人体危害极大,其对心血管的影响已得到充分解释,然而仍有一些否定数据需要得到解释。蛋白质组学作为一种有效的蛋白质分析技术,已广泛用于人类疾病的研究中。鉴于其在营养素研究中的成功应用,将其与反式脂肪酸的研究相结合,有利于找到新的突破点。本文就反式脂肪酸的来源、危害及蛋白质组学的研究进行综述。

关键词: 反式脂肪酸, 心血管疾病, 蛋白质组学

Abstract:

In recent years, a large number of studies have demonstrated that trans-fatty acids are harmful to human health, and the impact of trans-fatty acids on cardiovascular tissues have been fully evaluated. However, some negative data need to be explained. As an effective analytical technique, proteomics has been widely applied in the investigations of human diseases. Due to its successful application in the field of nutrients, we have undertaken the combinatorial studies of trans-fatty acids and proteomics, which will be benefited to explore a new breakthrough. In this paper, the source of trans-fatty acids, hazards and corresponding proteomics are reviewed.

Key words: trans-fatty acids, cardiovascular disease, proteomics

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