食品科学 ›› 2020, Vol. 41 ›› Issue (5): 323-330.doi: 10.7506/spkx1002-6630-20190228-225

• 专题论述 • 上一篇    下一篇

食品运载体系提高酚类物质生物利用度的研究进展

陈雨露,孙婉秋,高彦祥,毛立科,袁芳   

  1. (中国农业大学食品科学与营养工程学院,北京 100083)
  • 出版日期:2020-03-15 发布日期:2020-03-23
  • 基金资助:
    北京市自然科学基金项目(6192015);“十三五”国家重点研发计划重点专项(2016YFD0400804)

Recent Progress in Food Delivery Systems for Improving Bioavailability of Phenolic Compounds

CHEN Yulu, SUN Wanqiu, GAO Yanxiang, MAO Like, YUAN Fang   

  1. (College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China)
  • Online:2020-03-15 Published:2020-03-23

摘要: 酚类物质已被证实具有降低冠心病、糖尿病、癌症和其他慢性疾病患病率的功能,近年来,如何将其作为生物活性物质应用到在食品和药品领域受到广泛关注。然而酚类物质的低水溶性、低稳定性、被动扩散方式以及在胃肠道环境中的损失限制了其在人体内的生物利用度。目前解除这些限制的最佳方法就是基于食品运载体封装技术对酚类物质进行包埋,这种方法已被证实可有效提高活性成分的稳定性和生物利用度。本文介绍了酚类物质的功能性质和评价其生物利用度的常见方法,对现有的运载体系及其在提高酚类物质生物利用度方面的应用现状进行综述,最后针对目前研究中存在的问题对未来酚类物质运载体系的研究方向提出合理建议。

关键词: 酚类物质, 功能特性, 生物利用率, 消化模型, 运载体系

Abstract: Phenolic compounds have aroused particular interest in the food and pharmaceutical fields because they have been demonstrated to be associated with reduced incidences of coronary heart disease, diabetes, cancers, and other chronic diseases. However, extremely low absorption rate of phenolic compounds restricts their bioactivity in vivo. Such low absorption and bioavailability are due to their low water solubility, poor stability, passive diffusion, and active efflux in the gastrointestinal tract.?The best way to remove these limitations is to encapsulate phenolic compounds through food delivery systems, which can effectively improve the stability and bioavailability of active ingredients. This article outlines the functional properties of phenolic compounds and the common methods used for evaluating their bioavailability. Then, we summarize the existing food delivery systems used for improving the bioavailability of phenolic compounds. Finally, problems existing in this field of research are discussed and future research directions are proposed.

Key words: phenolic compounds, functional properties, bioavailability, digestion models, delivery systems

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