食品科学 ›› 2020, Vol. 41 ›› Issue (5): 290-298.doi: 10.7506/spkx1002-6630-20190408-078

• 专题论述 • 上一篇    下一篇

微囊藻毒素毒性及其作用机理研究进展

贺燕,黄先智,丁晓雯   

  1. (1.西南大学食品科学学院,重庆 400716;2.西南大学科技处,重庆 400716)
  • 出版日期:2020-03-15 发布日期:2020-03-23
  • 基金资助:
    现代农业产业技术体系建设专项(CARS-18)

Advances in Research on Toxicity and Mechanism of Action of Microcystins

HE Yan, HUANG Xianzhi, DING Xiaowen   

  1. (1. College of Food Science, Southwest University, Chongqing 400716, China;2. Science and Technology Department, Southwest University, Chongqing 400716, China)
  • Online:2020-03-15 Published:2020-03-23

摘要: 近年来,淡水水体富营养化引起的藻类大量繁殖及相关藻毒素污染已在世界范围内被广泛报道。微囊藻毒素(microcystins,MCs)是由微囊藻属、鱼腥藻属等藻类产生的有毒代谢产物,其分布广、结构稳定、毒性强,可通过饮用水、水产品和农作物等途径进入人体,对肝脏、肾脏、生殖系统、神经系统等具有毒性效应,对人体健康构成严重威胁。本文对MCs的毒性及其作用机理进行了综述与分析,对防治MCs对人体健康危害有一定的参考价值。

关键词: 微囊藻毒素, 毒性效应, 毒性作用机理

Abstract: In recent years, the excessive reproduction of harmful algae caused by the eutrophication of freshwater and the consequent algal toxin contamination have been widely studied worldwide. Microcystins (MCs), toxic metabolites produced by algae such as Microcystis and Anabaena, are widely distributed, and have stable structure and high toxicity. MCs can enter the human body through drinking water, aquatic products and crops, and have toxic effects on the liver, kidney, reproductive system and nervous system, posing a serious threat to human health. In this paper, the toxicity and mechanism of action of MCs are summarized and analyzed. We believe that this review can provide valuable information for preventing and controlling MCs from causing any harm to human health.

Key words: microcystins, toxic effects, toxicological mechanism

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