食品科学 ›› 2023, Vol. 44 ›› Issue (17): 363-381.doi: 10.7506/spkx1002-6630-20220923-246

• 专题论述 • 上一篇    下一篇

可生物降解食品接触材料中非有意添加物的鉴定和风险评估研究进展

胡云,刘源   

  1. (1.扬州市食品药品检验检测中心,江苏 扬州 225001;2.上海交通大学农业与生物学院,上海 200235)
  • 出版日期:2023-09-15 发布日期:2023-09-29
  • 基金资助:
    江苏省市场监督管理局科技计划资助项目(KJ207546)

Research Progress in the Identification and Health Risk Assessment of Non-intentionally Added Substances in Biodegradable Food Contact Materials

HU Yun, LIU Yuan   

  1. (1. Yangzhou Centre for Food and Drug Control, Yangzhou 225001, China; 2. School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 200235, China)
  • Online:2023-09-15 Published:2023-09-29

摘要: 绿色环保的可生物降解食品接触材料正得到越来越多的应用,但是,这种新型材料中存在原料和添加剂的降解产物、杂质、新形成的化合物和污染物,这些非有意添加物会迁移到食品中,其中许多化合物是未知物质,为了确保消费者的安全,有必要对其进行鉴定和风险评估。本文梳理了可生物降解食品接触材料中的非有意添加物及其可能的来源,概述了最新的样品前处理方法和高分辨质谱分析技术,介绍了毒理学关注阈值法在非有意添加物风险评估中的应用情况,提出生物测定法是常规风险评估方法的有效补充,以期为可生物降解食品接触材料的安全性研究提供参考。

关键词: 可生物降解食品接触材料;非有意添加物;鉴定;风险评估

Abstract: Green biodegradable food contact materials have been increasingly used, but they may contain degradation products from raw materials and additives, impurities, newly formed compounds and pollutants. These non-intentionally added substances, many of which are unknown, can migrate into foods. In order to ensure the safety of consumers, it is necessary to identify these substances and evaluate their health risks. This article summarizes non-intentionally added substances in biodegradable food contact materials and their possible sources, outlines the latest sample pretreatment methods and high-resolution mass spectrometry for the analysis of non-intentionally added substances, and describes the application of the threshold of toxicological concern approach in the health risk assessment of non-intentionally added substances. Moreover, this article proposes that bioassays are effective supplements to conventional risk assessment methods. It is hoped that this review will provide a reference for research on the safety of biodegradable food contact materials.

Key words: biodegradable food contact materials; non-intentionally added substance; identification; risk assessment

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