食品科学 ›› 2023, Vol. 44 ›› Issue (21): 368-385.doi: 10.7506/spkx1002-6630-20221026-274

• 专题论述 • 上一篇    

蛋白质-多糖非共价及共价复合物包埋活性成分的研究进展

梁洛丹, 曹伟伟, 李琳琳, 任广跃, 陈俊亮, 许韩山, 段续   

  1. (1.河南科技大学食品与生物工程学院,河南 洛阳 471000;2.杭州市临平区质量计量监测中心,浙江 杭州 311199)
  • 发布日期:2023-12-13
  • 基金资助:
    河南省外国知识分子专项引进项目(HNGD2021040);河南省高端外国专家引进计划项目(HNGD2022055); 河南省高等学校青年骨干教师培养计划项目(2020GGJS072)

Research Progress in Encapsulation of Bioactive Compounds in Protein-Polysaccharide Non-covalent and Covalent Complexes

LIANG Luodan, CAO Weiwei, LI Linlin, REN Guangyue, CHEN Junliang, XU Hanshan, DUAN Xu   

  1. (1. College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China; 2. Linping District, Hangzhou of Supervising Testing Center for Quality and Metrology, Hangzhou 311199, China)
  • Published:2023-12-13

摘要: 生物活性成分如多酚、类胡萝卜素等具有抗癌、抗氧化等多种健康功效,但这些活性成分在胃肠道环境中不稳定,易被破坏而无法充分发挥其健康功效。蛋白质和多糖通过非共价或共价相互作用可以形成蛋白质-多糖复合物,被广泛用作包埋活性成分的材料,以提高生物活性成分的稳定性和生理活性。本文综述了蛋白质和多糖形成复合物的类型,并介绍了反溶剂沉淀法、pH驱动法、热凝胶法和乳化法在蛋白质-多糖复合物递送活性成分中的应用,以期为蛋白质-多糖复合物包埋生物活性成分的研究与应用提供借鉴。

关键词: 蛋白质;多糖;相互作用;包埋;生物活性成分

Abstract: Bioactive ingredients such as polyphenols and carotenoids have various health benefits such as anti-cancer and antioxidant activities. However, bioactive components are unstable and easily damaged in the gastrointestinal environment, making them unable to fully exert their functional effects. Proteins and polysaccharides can form complexes via non-covalent or covalent interactions, which have been widely used as encapsulation materials to enhance the stability and activity of bioactive compounds. This review summarizes the types of protein-polysaccharide complexes, and describes the application of the anti-solvent, pH-driven, thermal gelation and emulsification methods for the delivery of bioactive ingredients by protein-polysaccharide complexes. It is anticipated that this review will provide a reference for the research and application of bioactive compounds encapsulated in protein-polysaccharide complexes.

Key words: protein; polysaccharide; interaction; encapsulation; bioactive component

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