食品科学 ›› 2025, Vol. 46 ›› Issue (12): 379-390.doi: 10.7506/spkx1002-6630-20241214-124

• 专题论述 • 上一篇    

酪蛋白胶束结构特性及其在递送领域应用的研究进展

叶晶莹,吴帆,张兆月,温馨,倪元颖,李茉   

  1. (中国农业大学食品科学与营养工程学院,国家果蔬加工工程技术研究中心,农业农村部果蔬加工重点实验室,北京 100083)
  • 出版日期:2025-06-25 发布日期:2025-05-23

Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery Systems

YE Jingying, WU Fan, ZHANG Zhaoyue, WEN Xin, NI Yuanying, LI Mo   

  1. (Key Laboratory of Fruit and Vegetable Processing, Ministry of Agriculture and Rural Affairs, National Engineering Research Center for Fruit and Vegetable Processing, College of Food Science and Nutrition Engineering, China Agricultural University, Beijing 100083, China)
  • Online:2025-06-25 Published:2025-05-23

摘要: 牛奶被认为是人类饮食中重要的蛋白质来源。作为牛奶中主要的蛋白质组分,酪蛋白因其自身结构存在的双亲性及自组装性能而引起学者们的广泛关注。但酪蛋白胶束的pH值、Ca2+、温度稳定性差的特点也限制了其在递送体系领域的应用。本文系统介绍了酪蛋白的结构种类、胶束结构的解析方式、基于胶束性质缺陷的改性方式及其后续应用,旨在证明酪蛋白基胶束作为生物活性递送系统的巨大潜力,并对未来酪蛋白胶束体系在功能性食品成分领域的发展前景提出展望。

关键词: 酪蛋白;胶束结构;包埋;疏水生物活性物质;改性

Abstract: Milk is considered an important source of protein in human diets. As the major protein component in milk, casein has attracted extensive attention from scholars due to its biparental structure and self-assembly properties. However, the poor pH, Ca2+, and temperature stability of casein micelles limit their application in delivery systems. This article systematically introduces the structural types of casein, the methods for its structural analysis, the methods for its modification based on the defects of micelle properties and their subsequent applications, aiming to prove the huge potential of casein micelles as delivery systems for bioactive compounds. Furthermore, this review provides an outlook on the future development of casein micelle systems in the field of functional food ingredients.

Key words: casein; micelle structure; encapsulation; hydrophobic bioactive substances; modification

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