食品科学 ›› 2025, Vol. 46 ›› Issue (18): 425-396.doi: 10.7506/spkx1002-6630-20250128-202

• 专题论述 • 上一篇    下一篇

茶叶缓解结肠炎及其机制研究进展

孙雨宁,刘倩芬,刘丹,李大祥,蔡荟梅,陈贵杰   

  1. (1.安徽农业大学 茶树种质创新与资源利用全国重点实验室,农业农村部茶树生物学与茶叶加工重点实验室,教育部茶叶化学与健康国际合作联合实验室,安徽 合肥 230036;2.安徽农业大学茶业学院,安徽?合肥 230036;3.安徽农业大学食品与营养学院,工业新茶饮绿色制造安徽省联合共建学科重点实验室,安徽省食品安全监测与品控重点实验室,安徽?合肥 230036;4.合肥综合性国家科学中心大健康研究院,安徽?合肥 230036)
  • 出版日期:2025-09-25 发布日期:2025-08-19
  • 基金资助:
    大健康研究院食品营养健康联合研究中心专项(2023SJY02);国家茶叶产业技术体系项目(CARS-19); 安徽农业大学引进与稳定人才项目(rc352220);国家自然科学基金青年科学基金项目(32001645)

Progress in Understanding the Role and Mechanism of Action of Tea in Alleviating Colitis

SUN Yuning, LIU Qianfen, LIU Dan, LI Daxiang, CAI Huimei, CHEN Guijie   

  1. (1. National Key Laboratory for Tea Plant Germplasm Innovation and Resource Utilization, Key Laboratory of Tea Biology and Tea Processing of Ministry of Agriculture and Rural Affairs, International Joint Research Laboratory of Tea Chemistry and Health Effects of Ministry of Education, Hefei 230036, China; 2. School of Tea Science, Anhui Agricultural University, Hefei 230036, China;3. Anhui Provincial Joint Construction Key Laboratory of Industrial New-Style Tea Beverage Green Manufacturing, Anhui Provincial Key Laboratory of Food Safety Monitoring and Quality Control, School of Food and Nutrition, Anhui Agricultural University, Hefei 230036, China; 4. Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei 230036, China)
  • Online:2025-09-25 Published:2025-08-19

摘要: 结肠炎(inflammatory bowel disease,IBD)是一类常见的慢性肠道炎症性疾病,主要包括溃疡性结肠炎和克罗恩病,其发病机制复杂,涉及多种因素的相互作用。近年来,茶叶及其活性成分在干预IBD及其作用机制方面的研究引起了广泛关注。研究表明,茶叶及其功能成分能够通过多种途径缓解结肠炎,包括调控炎症因子及相关信号通路、调节免疫功能、修复肠道屏障以及调节肠道菌群和代谢物等。本文综述了近年来茶叶缓解结肠炎的研究进展,重点探讨其作用机制,旨在为IBD的预防与治疗提供新的思路和科学依据。

关键词: 茶;活性成分;结肠炎;肠道菌群;作用机制

Abstract: Inflammatory bowel disease (IBD) is a common chronic intestinal inflammatory disorder, primarily including ulcerative colitis (UC) and Crohn’s disease (CD), with a complex pathogenesis involving multiple interacting factors. In recent years, intervention with tea and its active components in IBD and their action mechanisms have garnered considerable research attention. Research indicates that tea and its functional components can alleviate colitis through multiple pathways, including regulating inflammatory factors and related signaling pathways, modulating immune function, repairing the intestinal barrier, and regulating the gut microbiota and metabolites. This review summarizes recent progress on the role of tea in mitigating colitis, with a focus on its action mechanism, aiming to provide new insights and scientific evidence for the prevention and treatment of IBD.

Key words: tea; bioactive components; inflammatory bowel disease; gut microbiota; mechanism of action

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