食品科学 ›› 2026, Vol. 47 ›› Issue (4): 325-333.doi: 10.7506/spkx1002-6630-20250904-028

• 专题论述 • 上一篇    下一篇

天然产物功能因子情绪调节作用研究进展

崔竞雯,张香飞,刘新民,范蓓,王凤忠,卢聪   

  1. (1.中国农业科学院农产品加工研究所,北京 100193;2.山西农业大学食品科学与工程学院,山西 晋中 030801;3.宁波大学新药技术研究院,浙江 宁波 315000)
  • 出版日期:2026-02-25 发布日期:2026-03-16
  • 基金资助:
    “十四五”国家重点研发计划重点专项(2023YFD2201304);食品安全和营养健康高质量发展资政项目; 中国农业科学院农产品加工研究所创新工程项目(CAAS-ASTIP-2024-IFST)

Research Progress on the Emotion-Regulating Mechanism of Functional Factors of Natural Products

CUI Jingwen, ZHANG Xiangfei, LIU Xinmin, FAN Bei, WANG Fengzhong, LU Cong   

  1. (1. Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China; 2. College of Food Science and Engineering, Shanxi Agricultural University, Jinzhong 030801, China; 3. Institute of Drug Discovery Technology, Ningbo University, Ningbo 315000, China)
  • Online:2026-02-25 Published:2026-03-16

摘要: 情绪障碍是以情绪异常为主要症状的多种心理障碍的统称,包括抑郁症、焦虑症、强迫症等。其发病机制复杂多样,涉及神经递质失衡、神经内分泌功能异常、炎症和免疫系统异常等多个方面。随着研究的深入,越来越多的证据表明,天然产物中多种功能因子对预防和缓解情绪障碍具有积极作用。本文从神经递质失衡、神经炎症、下丘脑-垂体-肾上腺轴等方面总结了情绪障碍相关的可能发病机制,重点探讨天然产物功能因子在情绪障碍防控中的健康效应及作用,旨在为新型情绪调节健康产品的开发提供参考。

关键词: 天然产物功能因子;情绪障碍;健康效应;作用机制

Abstract: Emotional disorders represent a category of psychological conditions primarily defined by abnormal mood states, which include depression, anxiety, obsessive-compulsive disorder, and related syndromes. Their pathogenesis is multifactorial and complex, involving disturbances in neurotransmitter systems, neuroendocrine dysfunction, and abnormalities in inflammatory and immune responses. Recently, there has been accumulating evidence that various bioactive components derived from natural products can exert beneficial effects in the prevention and alleviation of emotional disorders. This article summarizes the potential pathogenic mechanisms underlying emotional disorders, focusing on neurotransmitter imbalance, neuroinflammation, and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, it emphasizes the effects of natural bioactive compounds on modulating and preventing mood disorders, aiming to provide a reference for the development of novel emotion-regulating health products.

Key words: functional factors of natural products; emotional disorders; health effects; mechanism of action

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