食品科学 ›› 2003, Vol. 24 ›› Issue (11): 123-125.

• 营养卫生 • 上一篇    下一篇

亚硫酸钠对小鼠骨髓PCE细胞微核的诱发及沙棘油的防护效应

 张波   

  1. 北京联合大学应用文理学院生物系
  • 出版日期:2003-11-15 发布日期:2011-12-13

In Vivo Study on Micronuclei Inducement by Sodiumin Sulfitein Mouse Bone Marrow and Role of Protection bySeabuckthorn Seed Oil

 ZHANG  Bo   

  1. The Biology Department of College of Arts and Sciences of Beijing Union Unversity
  • Online:2003-11-15 Published:2011-12-13

摘要: 采用腹腔注射染毒方式给予小鼠亚硫酸钠。实验结果表明,亚硫酸钠可引起小鼠骨髓嗜多染红细胞微核率显著增高,且呈明显的剂量效应关系。沙棘油对亚硫酸钠诱发的小鼠骨髓嗜多染红细胞微核率有明显的抑制作用。

关键词: 亚硫酸钠, 微核, 小鼠, 嗜多染红细, 沙棘油

Abstract: Micronuclei (MN) in ducement in the Polychromatophilic Erythroblasts (PCE) of mouse bone marrow by sodiuminsulfite was studied in vivo. It showed that the chemicals caused an increase of MN rate in the PCE cells in a dose-dependent manner.There was the protection effect of Seabuckthorn seed oil on the genetic damage induced by sodiumin sulfite.

Key words: sodiumin sulfite, micronuclei, mouse bone marrow, seabuckthorn seed oil