食品科学 ›› 2005, Vol. 26 ›› Issue (11): 230-233.

• 营养卫生 • 上一篇    下一篇

海藻糖提高动物热耐受性的研究

 葛宇, 宫衡, 刘玲, 赖承兴, 袁勤生   

  1. 上海市质量监督检验技术研究院,华东理工大学生物工程学院
  • 出版日期:2005-11-15 发布日期:2011-10-01

Study on Heat Endurance Effect of Trehalose Drinks on Mice

 GE  Yu, GONG  Heng, LIU  Ling, LAI  Cheng-Xing, YUAN  Qin-Sheng   

  1. 1.Shanghai Academe of Testing Technology on Quality Supervision; 2.Institute of Bioengineering, East China University of Science and Technology
  • Online:2005-11-15 Published:2011-10-01

摘要: 目的:探讨海藻糖提高热耐受能力的作用,为研制耐热型保健饮料提供依据。方法:以小鼠为模型,考察不同成分饮用水(水、蔗糖和海藻糖)饲喂的小鼠热暴露的存活时间和衰竭游泳时间。并比较了高温适应前后以及高温处理前后小鼠的一些生理生化指标如体重、血清中钾离子浓度、血糖含量和血红蛋白含量。结果:海藻糖能显著延长小鼠的热暴露存活时间。生理生化指标表明海藻糖具有抗脱水,能够在高温环境中维持细胞中钾离子浓度,有效维持血红蛋白含量。并且有一定储能作用。结论:海藻糖可以提高动物热耐受性,很有希望成为一种耐热保健饮料的成分。

关键词: 海藻糖, 热耐受性, 动物实验

Abstract: Objective: To study the effect of trehalose drinks on heat endurance of mice, so as to provide basis for developing a new heat endurance functional beverage. Methods: Using mouse which were fed by different drinks(water, sucrose water and trehalose water) respectively as testing animals which were exposed to 30℃ habitat. The surviving time upon heat exposure and the swimming time were examined and the physiologic and biochemical changes such as body weight, potassium concentration, blood sugar, hemoglobin were compared before and after heat exposure. Results:Trehalose could significantly improve the surviving time upon heat exposure, effectively sustain the hemoglobin level, and keep the potassium concentration in blood serum to protect cells from damage. Likewisly it could increase the blood sugar level and reserve energy. Conclusion: Trehalose could improve the heat endurance of the animal. So trehalose could be a good ingredient in heat sndurance drink.

Key words: trehalose, heat tolerance, animal test