小分子化合物高特异性识别体制备新技术

食品科学 ›› 2007, Vol. 28 ›› Issue (1): 369-369.

小分子化合物高特异性识别体制备新技术

杨金易, 王弘, 潘科, 孙远明

广东省教育厅食品质量与安全重点实验室华南农业大学食品质量与安全研究所；广东省教育厅食品质量与安全重点实验室；华南农业大学食品质量与安全研究所；广东广州510642；

出版日期:2007-01-15 发布日期:2011-12-31

The New Technique for Preparation Aptamer of Binding Small Molecules Compound with High Specificity

YANG Jin-Yi, WANG Hong, PAN Ke, SUN Yuan-Ming

Key Laboratory of Food Quality and Safety of Education Department of Guangdong Province, Research Institute of Food Quality and Safety , South China Agricultural University, Guangzhou 510642, China

Online:2007-01-15 Published:2011-12-31

摘要/Abstract

摘要： 无论在医学领域还是在食品安全领域小分子化合物的识别与检测已成为目前研究的热点和难点,抗体在识别小分子化合物上还存在许多不足,SELEX技术与Anticalin制备技术的出现为小分子化合物识别带来了希望,本文主要介绍了SELEX技术与Anticalin制备技术的原理特点及其研究进展与应用。

关键词: SELEX技术, Anticalin制备技术, 小分子化合物

Abstract: Now it is focus and nodus that identify and detection of mall molecules compound in the medicine and food safety field. Antibody show deficiency in detection of mall molecules compound, it is hope that the technique appearance of SELEX and Anticalin. The recent advances in the SELEX and Anticalin technique are reviewed.

Key words: SELEX technique, Anticalin technique, small molecules compound

杨金易, 王弘, 潘科, 孙远明. 小分子化合物高特异性识别体制备新技术[J]. 食品科学, 2007, 28(1): 369-369.

YANG Jin-Yi, WANG Hong, PAN Ke, SUN Yuan-Ming. The New Technique for Preparation Aptamer of Binding Small Molecules Compound with High Specificity[J]. FOOD SCIENCE, 2007, 28(1): 369-369.