食品科学 ›› 2008, Vol. 29 ›› Issue (9): 547-549.

• 营养卫生 • 上一篇    下一篇

油菜蜂花粉及其提取物对小鼠免疫功能的影响

 孙丽萍, 廖磊, 王大仟, 彭文君   

  1. 中国农业科学院蜜蜂研究所; 北京市卫生局临床药学研究所;
  • 出版日期:2008-09-15 发布日期:2011-12-08

Effects of Rape Bee Pollen and Its Different Extracts on Immune Function in Mice

 SUN  Li-Ping, LIAO  Lei, WANG  Da-Qian, PENG  Wen-Jun   

  1. 1. Bee Research Institute,Chinese Academy of Agricultural Sciences,Beijing 100093,China; 2. Institute of Beijing Health Administration Clinical Pharmacy,Beijing 100035,China
  • Online:2008-09-15 Published:2011-12-08

摘要: 为观察油菜蜂花粉及其提取物在小鼠体内的免疫调节作用,进行免疫低下小鼠碳廓清实验与小鼠DTH超敏反应实验。结果显示,在碳廓清实验中,花粉组、提取物A、C、D组吞噬指数(a)较模型组有明显升高(p<0.05与p<0.01),其中提取物A的碳廓清指数(K)较模型组有明显升高(p<0.05)。在小鼠DTH超敏反应实验中,花粉及其提取物组各组对小鼠DTH超敏反应均有抑制作用(p<0.05与p<0.01)。本实验说明油菜蜂花粉及其提取物具有调节免疫功能的作用。

关键词: 油菜蜂花粉, 花粉提取物, 免疫功能

Abstract: In order to investigate the effects of rape bee pollen and its different extracts on immune function in mice, delayed- type hypersensitivity (DTH) and macrophage phagocytic function were studied. The results showed that compared with the model group, phagocytosis index (a) increases significantly in group rape bee pollen and extract A, C and D (p<0.05, p<0.01), and the carbon clearance index (K) also increases significantly in group extract A (p<0.05). The immediate hypersensitivity is inhibited by rape bee pollen and its different extracts. These indicated that rape bee pollen and its different extracts have effects of regulating immune function.

Key words:  , rape bee pollen; extracts of rape bee pollen; immune function;