玉米黄色素防治白内障的动物实验研究

食品科学 ›› 2008, Vol. 29 ›› Issue (9): 595-597.

玉米黄色素防治白内障的动物实验研究

曹龙奎, 孟令

黑龙江八一农垦大学食品学院黑龙江省农产品加工工程技术研究中心；

出版日期:2008-09-15 发布日期:2011-12-08

Experimental Study of Preventive and Therapeutic Effects of Maize Yellow Pigment on Cataract of Rats

CAO Long-Kui, MENG Ling

College of Food Science and Engineering,Heilongjiang August First Land Reclamation University,Agri-food Processing Development Centre of Heilongjiang,Daqing 163319,China

Online:2008-09-15 Published:2011-12-08

摘要/Abstract

摘要： 目的:观察玉米黄色素对大鼠白内障的防治作用。方法:用半乳糖诱发大鼠白内障,喂饲玉米黄色素进行了实验研究。实验观察了大鼠眼晶体混浊度、测定了眼晶体内的SOD(超氧化物歧化酶)和MDA(丙二醛)水平。由实验可知,模型组在实验第30d时,已经有81.25%的眼晶体是Ⅲ期白内障,玉米黄色素各组在实验第30d时没有眼晶体发生Ⅲ期白内障,而发生Ⅱ期白内障的眼晶体仅为31.25%和43.75%,结果表明,玉米黄色素能有效地延缓受试大鼠白内障进展,降低眼晶体混浊度。生化指标也显示,玉米黄色素各组与模型组相比,眼晶状体SOD活力显著升高了40.55%～50.02%,MDA含量显著降低了31.84%～38.89%,说明玉米黄色素能提高眼晶体SOD的含量,降低眼晶体MDA的含量,即减轻眼晶体脂质过氧化损伤。结论:玉米黄色素具有保护晶体抗氧化防御体系的功能,能延缓和控制白内障的形成,对早期白内障有一定的防治作用。

关键词: , 白内障, 玉米黄色素, 半乳糖, SOD, MDA

Abstract: Objective:To investigate the preventive and therapeutic effects of maize yellow pigment on cataract of rats. Methods: The experiment was conducted by inducing the cataract of rats with galactose and raising the rats with maize yellow pigment. The turbidity of ocular lens was observed, and the level of SOD (superoxide dismutase) of ocular lens and MDA were determined. In the first 30 days of the experiment, model group has 81.25 % of ocular lens reaching phase Ⅲ of cataract already, and maize yellow pigment groups have no ocular lens reaching phase Ⅲ of cataract, however, only 31.25 % and 43.75 % of ocular lens reach aseⅡof cataract. The results showed that maize yellow pigment can delay the progress of cataract of rats and diminish turbidity of ocular lens effectively. Compared with model group, biochemical indexes indicated that the SOD activities of eye crystalline lens of maize yellow pigment groups increase by 40.55%～50.02%, and MDA contents decrease by 31.84 %～38. 89 %. The results showed that maize yellow pigment can raise the SOD content of eye crystalline lens, and reduce the MDA content in it. That means that it can lessen lipid peroxide damage of eye crystalline lens. Conclusion:Maize yellow pigment has the function of antioxidant defense system that protects crystalline lens. And it can delay and control the formation of cataract, and also prevent and cure the early cataract.

Key words: cataract, maize yellow pigment, galactose, SOD, MDA

曹龙奎, 孟令. 玉米黄色素防治白内障的动物实验研究[J]. 食品科学, 2008, 29(9): 595-597.

CAO Long-Kui, MENG Ling. Experimental Study of Preventive and Therapeutic Effects of Maize Yellow Pigment on Cataract of Rats[J]. FOOD SCIENCE, 2008, 29(9): 595-597.

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