食品科学 ›› 2021, Vol. 42 ›› Issue (17): 343-349.doi: 10.7506/spkx1002-6630-20200826-356

• 专题论述 • 上一篇    下一篇

非变性II型胶原蛋白研究进展

杨舒乔,王迪,高彦祥   

  1. (中国农业大学食品科学与营养工程学院,北京 100083)
  • 发布日期:2021-09-29
  • 基金资助:
    北京市科学技术委员会科技计划项目(Z181100009218002)

Progress in Undenatured Type II Collagen

YANG Shuqiao, WANG Di, GAO Yanxiang   

  1. (College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China)
  • Published:2021-09-29

摘要: 非变性II型胶原蛋白是指经提取后仍能保留完整大分子胶原蛋白三螺旋结构的II型胶原蛋白,在类风湿性关节炎和骨关节炎的预防和治疗中极具开发应用价值。II型胶原蛋白广泛存在于动物软骨组织中,与蛋白聚糖紧密结合。本文介绍了非变性II型胶原蛋白的功能与结构,结合近年来国内对非变性II型胶原蛋白的研究,从提取方法、定性定量表征方法及在食品领域的应用现状等方面进行综述,为非变性II型胶原蛋白的进一步精深加工及其综合利用提供参考。

关键词: 非变性II型胶原蛋白;提取;功能;应用

Abstract: Undenatured type II collagen is a type II collagen that can retain the triple helix structure after extraction, and it has great potential in the prevention and treatment of osteoarthritis and rheumatoid arthritis. Type II collagen is widely present in animal cartilage tissues and is tightly combined with proteoglycans. This article introduces readers to the function and structure of undenatured type II collagen, and reviews the methods for the extraction, and qualitative and quantitative characterization of undenatured type II collagen and the current status of its application in the food industry, with the aim of providing references for further processing and comprehensive utilization of undenatured type II collagen.

Key words: undenatured type II collagen; extraction; function; application

中图分类号: