食品科学 ›› 2021, Vol. 42 ›› Issue (3): 339-345.doi: 10.7506/spkx1002-6630-20200209-071

• 专题论述 • 上一篇    下一篇

沙门氏菌检测生物传感器研究进展

吴有雪,吴美娇,田亚晨,王政,郭亮,刘程,方水琴,刘箐   

  1. (上海理工大学医疗器械与食品学院,上海 200093)
  • 发布日期:2021-02-25
  • 基金资助:
    上海市科技创新行动计划农业领域项目(19391902000);国家自然科学基金面上项目(31871897)

Progress in the Development of Salmonella Biosensors

WU Youxue, WU Meijiao, TIAN Yachen, WANG Zheng, GUO Liang, LIU Cheng, FANG Shuiqin, LIU Qing   

  1. (School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China)
  • Published:2021-02-25

摘要: 沙门氏菌(Salmonella)是最常见的食源性致病菌之一,传统的沙门氏菌检测方法包括分离培养和生化鉴定、免疫分析法、核酸分析法等,其可靠性高,但检测限低、繁琐且费时。传感器是整合生物学、化学、光学等技术的新型快速检测技术。本文对比了沙门氏菌的传统检测方法,重点分析了近几年来基于纳米材料、适配体的光学或电化学沙门氏菌生物传感器检测的新方法,并对沙门氏菌检测生物传感器的未来发展趋势进行了综述与展望。

关键词: 沙门氏菌;生物传感器;检测技术

Abstract: Salmonella is one of the most common foodborne pathogens, and the traditional methods for Salmonella detection include biochemical identification following isolation and culture, immunoassay, and nucleic acid analysis, which, despite having high reliability, have low detection limits and are tedious and time-consuming. The biosensor is a new technology for rapid detection of Salmonella integrating biology, chemistry, optics and other technologies. This review presents a comparison of the traditional methods for Salmonella detection, and it focuses on describing the optical and electrochemical biosensors based on nanomaterials and aptamers. Finally, we conclude with an outlook on the future development of biosensors for Salmonella detection.

Key words: Salmonella; biosensor; detection technology

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