食品科学 ›› 2021, Vol. 42 ›› Issue (9): 214-221.doi: 10.7506/spkx1002-6630-20200407-090

• 专题论述 • 上一篇    下一篇

用于叶酸检测的荧光传感器构建及应用研究进展

李伊宁,黄昆仑,姚志轶   

  1. (中国农业大学食品科学与营养工程学院,北京 100083)
  • 出版日期:2021-05-15 发布日期:2021-06-02
  • 基金资助:
    国家自然科学基金面上项目(31871877);中国农业大学2018年本科生科研训练计划项目

Progress in the Construction and Application of Fluorescence Sensors for the Detection of Folic Acid

LI Yining, HUANG Kunlun, YAO Zhiyi   

  1. (College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China)
  • Online:2021-05-15 Published:2021-06-02

摘要: 叶酸是一种水溶性B族维生素。快速且准确地检测叶酸是保证食品药品安全有效的重要手段,也是辅助临床诊断的有效途径。近年来,基于荧光传感器的叶酸检测方法因其更快的响应速度、更高的灵敏度和便捷性而受到广泛关注。本文按照构建检测叶酸用荧光传感器所用的材料进行分类,对不同类型传感器的构建及其特点进行综述。此外,介绍了这些传感器在食品药品质量控制、临床检测评估和细胞成像等方面的应用情况,并对其发展方向和应用前景进行了展望。

关键词: 叶酸;荧光传感器;质量控制;分析检测

Abstract: Folic acid is a water-soluble B vitamin. The rapid and accurate detection of folic acid is of great significance for ensuring the safety and effectiveness of food and medicine and assisting in the clinical diagnosis of diseases. In recent years, folic acid sensors based on fluorescent probes have received more and more attention due to their fast response, high sensitivity and convenience. In this review, the construction and characteristics of fluorescence sensors based on different sensing materials for the detection of folic acid are summarized. Moreover, the application of these sensors in food and drug quality control, clinical detection and evaluation, and cell imaging is reviewed. Finally, future directions and prospects are discussed.

Key words: folic acid; fluorescence sensor; quality control; analysis and detection

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