食品科学 ›› 2024, Vol. 45 ›› Issue (16): 303-310.doi: 10.7506/spkx1002-6630-20230601-006

• 专题论述 • 上一篇    

丙酮酸激酶翻译后修饰影响肉品质研究进展

黄小兰,陈丽,任驰,摆玉蔷,侯成立,李欣,罗瑞明,张德权   

  1. (1.宁夏大学食品科学与工程学院,宁夏 银川 750021;2.中国农业科学院农产品加工研究所,农业农村部农产品质量安全收贮运管控重点实验室,北京 100193)
  • 发布日期:2024-08-06
  • 基金资助:
    国家自然科学基金面上项目(32072144)

Research Progress on the Effect of Post-translational Modification of Pyruvate Kinase on Meat Quality

HUANG Xiaolan, CHEN Li, REN Chi, BAI Yuqiang, HOU Chengli, LI Xin, LUO Ruiming, ZHANG Dequan   

  1. (1. College of Food Science and Engineering, Ningxia University, Yinchuan 750021, China; 2. Key Laboratory of Agro-products Quality and Safety in Harvest, Storage, Transportation, Management and Control, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China)
  • Published:2024-08-06

摘要: 畜禽宰后肌肉向肉的转变过程会经历一系列生化反应,其中蛋白质翻译后修饰是影响肉品质的关键因素。糖酵解是宰后肌肉的主要供能途径,丙酮酸激酶作为糖酵解限速酶,蛋白质翻译后修饰通过改变其功能和结构而影响肉品质。本文以丙酮酸激酶的结构和功能为切入点,综述丙酮酸激酶翻译后修饰对其功能结构的影响和丙酮酸激酶磷酸化、乙酰化及S-亚硝基化影响肉品质的研究进展。

关键词: 肉;丙酮酸激酶;磷酸化;乙酰化;S-亚硝基化;糖酵解

Abstract: The postmortem conversion of muscle to meat goes through a series of complex physiological and biochemical changes, among which protein post-translational modifications (PTMs) are key factors affecting meat quality. Glycolysis is the major energy supply pathway in postmortem muscle. PTMs can change the function and structure of pyruvate kinase, a rate-limiting enzyme in the glycolytic pathway, which can in turn affect meat quality. Beginning with an overview of the structure and function of pyruvate kinase, this article reviews the recent research progress on the effects of PTMs of pyruvate kinase on its function and structure and the effects of pyruvate kinase phosphorylation, acetylation and S-nitrosylation on meat quality.

Key words: meat; pyruvate kinase; phosphorylation; acetylation; S-nitrosylation; glycolysis

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