食品科学 ›› 2024, Vol. 45 ›› Issue (22): 361-372.doi: 10.7506/spkx1002-6630-20240412-116

• 专题论述 • 上一篇    

基于碳点的荧光适配体传感器在食品安全检测中的应用研究进展

谢希杨, 黄天然, 黄明   

  1. (1.青海高等职业技术学院,青海 海东 810700;2.南京黄教授食品科技有限公司,国家禽肉加工技术研发专业中心,江苏省畜禽产品加工工程技术研究中心,江苏 南京 211200;3.南京农业大学食品科学技术学院,江苏 南京 210095)
  • 出版日期:2024-11-25 发布日期:2024-11-05

Research Progress in the Application of Carbon Dot-Based Fluorescent Aptamer Sensors in Food Safety Detection

XIE Xiyang, HUANG Tianran, HUANG Ming   

  1. (1. Qinghai Higher Vocational and Technical College, Haidong 810700, China; 2. Nanjing Huangjiaoshou Food Science and Technology Co. Ltd., National R&D Center for Poultry Processing Technology, Jiangsu Research Center for Livestock and Poultry Products Processing Engineering and Technology, Nanjing 211200, China; 3. College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China)
  • Online:2024-11-25 Published:2024-11-05

摘要: 碳点(carbon dots,CDs)是一种新型的碳基纳米材料,具有出色的荧光特性和毒性低、碳前体来源丰富等优点。适配体(aptamer,Apt)可以特异性结合靶标,应用于传感器能大幅提高检测精度和灵敏度。以CDs作为信号转导元件,以Apt作为目标识别元件构建的荧光生物传感器引起了学者们的关注。本文综述了CDs的结构、分类、荧光特性和Apt的优点,重点介绍了基于CDs的荧光Apt传感器的构建策略及其在食品安全检测中的应用现状及进展,旨在为食品质量监管、食品安全现场快速检测技术等领域的研究提供参考。

关键词: 碳点;适配体;荧光生物传感器;快速检测技术;食品安全

Abstract: Carbon dots (CDs) are a new type of carbon-based nanomaterials with excellent fluorescence properties, low toxicity, which offer an abundant source of carbon precursors. An aptamer (Apt) can specifically bind to its target molecule, and its application in sensors can dramatically improve the detection accuracy and sensitivity. Fluorescent biosensors with CDs as the signal transduction element and Apt as the target recognition element have attracted attention from researchers. In this paper, we review the structure, classification, fluorescence properties of CDs and the advantages of Apt, with a focus on the strategies for constructing fluorescent Apt sensors based on CDs and the current status and recent progress in their application in food safety detection, aiming to provide a reference for research in the fields of food quality supervision and on-site rapid detection technology for food safety.

Key words: carbon dots; aptamer; fluorescent biosensors; rapid detection technology; food safety

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