食品科学 ›› 2010, Vol. 31 ›› Issue (1): 76-78.doi: 10.7506/spkx1002-6630-201001017

• 基础研究 • 上一篇    下一篇

大孔树脂对脂蛋白的吸附研究

丁勇   

  1. 上海海洋大学食品学院
  • 收稿日期:2009-03-20 出版日期:2010-01-01 发布日期:2014-05-19
  • 通讯作者: 丁勇 E-mail:yding@shou.edu.cn
  • 基金资助:

    上海市教委优青基金项目(科07-23);上海市海洋大学博士启动基金项目(06337)

Adsorption of Lipoprotein onto Macroporous Resin

DING Yong   

  1. College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China
  • Received:2009-03-20 Online:2010-01-01 Published:2014-05-19
  • Contact: DING Yong E-mail:yding@shou.edu.cn

摘要:

对大孔吸附树脂对低密度脂蛋白(LDL)的体外吸附过程进行研究。对3 种大孔树脂在相同的实验条件下进行小牛血清的脂蛋白吸附,通过比较3 种树脂对LDL 的吸附能力,选取出较适宜进行LDL 吸附的大孔树脂D113。然后在吸附柱上进行动态吸附,并通过数学模型进行吸附过程的描述。结果表明:模型的描述与实验结果相一致,对吸附过程的设计和实验有一定的参考价值。

关键词: 大孔树脂, 低密度脂蛋白, 高密度脂蛋白, 吸附

Abstract:

In this study, in vitro adsorption process of low density lipoprotein (LDL) onto macroporous resin was investigated. Lipoprotein from calf serum was used as the material to conduct adsorption experiments by 3 kinds of macroporous resins. The optimal resin was screened in terms of adsorption capacity towards LDL. Results indicated that macroporous resin D113 exhibited the highest adsorption capacity. Meanwhile, dynamic adsorption process was also described using a mathematical mode, which could well fit experimental data. Therefore, this model will provide practical reference for further research of LDL adsorption.

Key words: macroporous resin, low density lipoprotein (LDL), high density lipoprotein (HDL), adsorption

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