燕麦β-葡聚糖对高脂血症大鼠空腹和餐后脂代谢的影响

doi:10.7506/spkx1002-6630-200901062

食品科学 ›› 2009, Vol. 30 ›› Issue (1): 258-260.doi: 10.7506/spkx1002-6630-200901062

燕麦β-葡聚糖对高脂血症大鼠空腹和餐后脂代谢的影响

申瑞玲^{1 , 2}，王志瑞^{1 ,*} ，董吉林²，李宏全^1，李文全¹

1.山西农业大学动物科技学院 2.郑州轻工业学院食品与生物工程学院

收稿日期:2008-01-04 出版日期:2009-01-01 发布日期:2010-12-29
通讯作者: 申瑞玲 E-mail:shenruiling2002@yahoo.com.cn
基金资助:
山西省科技机关计划项目(051072)；国家自然科学基金项目(20776135)

Effects of Oat β-Glucan on Limosis and Postprandial Lipid Metabolism of Hyperlipidemic Rats

SHEN Rui-ling1,2，WANG Zhi-rui1,*，DONG Ji-lin2，LI Hong-quan1，LI Wen-quan1

(1.College of Animal Science and Technology, Shanxi Agricultural University, TaiGu 030801, China；
2.School of Food and Biological Engineering, Zhengzhou Institute of Light Industry, Zhengzhou 450002,China)

Received:2008-01-04 Online:2009-01-01 Published:2010-12-29
Contact: SHEN Rui-ling1 E-mail:shenruiling2002@yahoo.com.cn

摘要/Abstract

摘要：

研究了燕麦β- 葡聚糖对高脂血症大鼠空腹和餐后脂代谢的影响。58 只雄性SD 大鼠随机分为基础组(n=10)和模型组(n=40)，分别饲喂基础饲料和高脂饲料，饲养3w 后，将造模成功的高血脂症大鼠随机分为高脂对照组、添加燕麦β- 葡聚糖低剂量组、中剂量组和高剂量组，每组10 只，分别饲喂含0、6、12、24g β- 葡聚糖/kg 的高脂饲料6w。于实验期末，分别测定大鼠空腹(禁食12h)和餐后(禁食16h 后再强饲5g 饲料后2h)血浆TC、TG、LDL-C、HDL-C、ApoAI 和ApoB 的含量以及肝脏脂质变化。结果表明：不同剂量β- 葡聚糖都极显著降低空腹血浆TC 、LDL-C 和ApoB 水平，而对HDL-C、TG 和ApoAI 无显著影响；β- 葡聚糖可以改善餐后血脂分布，降低肝脏脂质含量，不同剂量之间具有一定的差异性。

关键词: 燕麦β-葡聚糖, 大鼠, 空腹和餐后, 脂代谢

Abstract:

Fifty-eight male SD rats were randomly divided into two groups, the control group (n=10) fed with basal diets and the model group (n=48) fed with high-fat diets for 3 weeks. Then hyperlipidemia rats were divided into 4 treatments (n=10), high lipid control treatment, low-dose, medium-dose and high-dose oat β-glucan treatments, which were fed high-fat diets plus different contents of oat β-glucan (0, 6,12 and 24 g β-glucan/kg, respectively) for 6 weeks. The levels of TC, TG, LDL-C , HDLC, ApoAI and ApoB in plasma were measured at the states of limosis (Rats were fasted for 12 h) and postprandial 2 h (Rats were fasted for 16 h and then fed 5 g diet), respectively. Hepatic lipids were also measured at the end of experiments. The results showed that compared with high lipid control group, the contents of TC, LDL-C and ApoB in plasma are significantly decreased in three oat β-glucan groups of hypolipidemic rats at the state of limosis. Three doses of β-glucan also can significantly improve postprandial plasma lipid distribution and reduce hepatic cholesterol and triglyceride concentrations. Furthermore, the difference among three doses of oat β-glucan was observed in this experiment.

Key words: oat β-glucan, limosis and postprandial lipid metabolism

中图分类号:

R151

申瑞玲1,2，王志瑞1,*,董吉林2，李宏全1，李文全1. 燕麦β-葡聚糖对高脂血症大鼠空腹和餐后脂代谢的影响[J]. 食品科学, 2009, 30(1): 258-260.

SHEN Rui-ling1,2，WANG Zhi-rui1,*，DONG Ji-lin2，LI Hong-quan1，LI Wen-quan1. Effects of Oat β-Glucan on Limosis and Postprandial Lipid Metabolism of Hyperlipidemic Rats[J]. FOOD SCIENCE, 2009, 30(1): 258-260.

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燕麦β-葡聚糖对高脂血症大鼠空腹和餐后脂代谢的影响

Effects of Oat β-Glucan on Limosis and Postprandial Lipid Metabolism of Hyperlipidemic Rats

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