食品科学 ›› 2004, Vol. 25 ›› Issue (7): 52-55.

• 基础研究 • 上一篇    下一篇

非生物性因素对壳聚糖抗菌活性的影响

 吴俊, 夏文水   

  1. 江南大学食品学院
  • 出版日期:2004-07-15 发布日期:2011-10-24

Study on Abiotic Factors Effects on Antibacterial Activities of Chitosan

 WU  Jun, XIA  Wen-Shui   

  1. Food College of Southern Yountze University
  • Online:2004-07-15 Published:2011-10-24

摘要: 以具有代表性的两类病原菌:金黄色葡萄球菌和大肠杆菌为实验菌种,研究了不同的酸溶液、金属离子、离子强度和pH等非生物性因素对壳聚糖抗菌活性的影响。结果表明:在壳聚糖的酸溶液中,低碳数的有机酸比高碳数的有机酸和常见的无机酸更有利于壳聚糖抗菌活性的发挥;在pH6.0的环境中,壳聚糖的抗菌活性最强;由于与壳聚糖的螯合作用,Zn2+的加入对于壳聚糖的抗菌效率影响最大,Mg2+的影响相对最小;离子强度的增大可以更好地提高壳聚糖的抗菌活性。

关键词: 壳聚糖, 非生物性因素, 抗菌活性, 病原菌

Abstract: The effects of abiotic factors such as acid solvent、metal ion、ion strength and pH on the antibacterial activitiesof chitosan were investigated by using two kinds of typical pathogens: Escherichia coli and Staphylococcus aureus as testmicroorganisms. The results showed that organic acids with low carbon number are better solvents for chitosan than those inorganicacid. pH6.0 was optimum to the antibacterial activity of chitosan oweing to the chelating capacity of chitosan toward metal ions.The addition of Zn2+ ions inhibited the antibacterial activity of chitosan the most, while the addition of Mg2+ ions inhibited theantibacterial activity of chitosan the least. The antibacterial activity of chitosan increased with ionic strength.

Key words: chitosan, abiotic factor, antibacterial activity, pathogen