关键词: 雷竹笋, 膳食纤维, 超微化, 高脂血症小鼠, 血脂水平

Abstract: In this study, we determined the effect of superfine powders of dietary fiber from Phyllostachys praecox shoots (PPDF) prepared by three different grinding methods on high-fat diet-induced hyperlipidemia in mice. The hyperlipidemic mice were administered by gavage with a suspension of each superfine powder in distilled water at a dose of 2.5 g/(kg·d mb) by gavage (20 mL/kg). The results showed that compared with the normal control group, the body mass of mice in the model group significantly increased (P < 0.05); serum total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), atherosclerosis index (AI), and fat/body mass ratio increased significantly (P < 0.01), whereas high density lipoprotein cholesterol (HDL-C) was significantly lower (P < 0.01); superoxide dismutase (SOD) activity and malondialdehyde (MDA) content in both serum and liver tissue decreased and increased, respectively (P < 0.05); and in the feces, dry and hard, water content decreased, while fecal fat and cholesterol levels increased (P < 0.05). Compared with the model control group, PPDF significantly reduced body mass, serum lipid level and fat/body mass ratio of mice but increased HDL-C (P < 0.01). In addition, PPDF enhanced SOD activity and decreased MDA content in serum and liver tissue (P < 0.05), increased fecal water content, and reduced the levels of fecal fat and cholesterol (P < 0.05). Moreover, at the same dose, the smaller the particle size of PPDF the more obvious its effect on hyperlipidemic mice. In conclusion, this study indicates that PPDF can improve hyperlipidemia.

Key words: Phyllostachys praecox shoots, dietary fiber, superfine grinding, hyperlipidemic mice, blood lipid level