食品科学 ›› 2021, Vol. 42 ›› Issue (13): 265-272.doi: 10.7506/spkx1002-6630-20200623-313

• 专题论述 • 上一篇    下一篇

大豆活性组分和肠道菌群相互作用研究进展

吴雪娇,赵力超,方祥,郭颖瑜,梁文欧,马宇昊,王丽   

  1. (华南农业大学食品学院,广东 广州 510642)
  • 出版日期:2021-07-15 发布日期:2021-07-27
  • 基金资助:
    国家自然科学基金面上项目(31771940);广州市基础与应用基础研究项目(202002030264); 广东省自然科学基金面上项目(2020A1515011561)

Progress in Understanding the Interaction between Bioactive Components of Soybean and Gut Microbiota

WU Xuejiao, ZHAO Lichao, FANG Xiang, GUO Yingyu, LIANG Wen’ou, MA Yuhao, WANG Li   

  1. (College of Food Science, South China Agricultural University, Guangzhou 510642, China)
  • Online:2021-07-15 Published:2021-07-27

摘要: 目前食品组分与肠道菌群的相互作用及其对健康的影响已成为膳食与健康领域的研究热点。存在于动物体内的肠道菌群对大豆活性组分的分解代谢、转化吸收有着重要作用,大豆活性组分在体内肠道菌群作用下发生生物转化,导致其结构改变,从而形成新的活性成分,进而影响人体健康。同时,大豆活性组分的肠道菌群代谢产物又能够调节肠道菌群结构、保护肠黏膜屏障、维护肠道微生态平衡。本文对大豆活性组分如何在菌群作用下进行有效生物转化、肠道菌群在外源组分的扰动下如何进行菌群结构和丰度调整以及大豆组分的菌群代谢产物对人的健康影响等方面进行了综述,以期为深入研究大豆活性成分对人体健康作用的机理提供参考。

关键词: 大豆;肠道菌群;活性组分;健康

Abstract: At present, the interaction between food components and gut microbiota as well as its effect on health is a research hotspot in the field of diet and health. The gut microbiota of humans plays an important role in the catabolism, transformation and absorption of bioactive components from soybean, and bioactive components of soybean can be biotransformed by the gut microbiota, causing structural changes to form new bioactive ingredients, which can benefit human health. Moreover, metabolites generated by the gut microbiota from bioactive components of soybean can regulate the structure of the gut microbiota, protect the intestinal mucosa barrier, and maintain the intestinal microecological balance. In this paper, how soybean bioactive components are biotransformed by the gut microbiota, how the abundance and community structure of gut microbiota under exogenous disturbances are regulated, and the health benefits of metabolites generated by the gut microbiota from soybean bioactive components are reviewed, in order to provide a basis for in-depth research on the mechanism underlying the health benefits of soybean bioactive ingredients.

Key words: soybean; gut microbiota; bioactive components; health

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