食品科学 ›› 2021, Vol. 42 ›› Issue (21): 372-379.doi: 10.7506/spkx1002-6630-20200817-212

• 专题论述 • 上一篇    

乳脂肪球膜的特性、开发及在模拟母乳脂肪球结构中的应用

李晓东,潘悦,刘璐,朱启鹏   

  1. (1.东北农业大学食品学院,黑龙江 哈尔滨 150030;2.东北农业大学 乳品科学教育部重点实验室,黑龙江 哈尔滨 150030)
  • 出版日期:2021-11-15 发布日期:2021-11-23
  • 基金资助:
    黑龙江省“百千万”工程科技重大专项(2019ZX07801-3); 中国食品科学技术学会食品科技基金——雅培食品营养与安全专项科研基金项目(CAJJ-1-1)

Characteristics and Development of Milk Fat Globule Membrane and Its Applications in Simulating Human Milk Fat Globule Structure

LI Xiaodong, PAN Yue, LIU Lu, ZHU Qipeng   

  1. (1. School of Food Science, Northeast Agricultural University, Harbin 150030, China; 2. Key Laboratory of Dairy Science of Ministry of Education, Northeast Agricultural University, Harbin 150030, China)
  • Online:2021-11-15 Published:2021-11-23

摘要: 乳脂肪球膜(milk fat globule membrane,MFGM)是包裹在天然乳脂肪球外部的3 层膜状结构,然而牛乳基和大豆基婴儿配方奶粉缺少MFGM,脂肪球结构与母乳存在较大差异,因此添加外源MFGM以及制备与母乳脂肪球结构接近的婴儿配方奶粉成为了近期的研究焦点。本文综述了MFGM的相关特性和生产开发途径,以及牛乳MFGM在仿母乳脂肪球结构乳液和婴儿配方奶粉中的应用。体外模拟婴儿胃肠道消化实验以及啮齿动物体内实验结果表明,仿母乳脂肪球结构乳液和婴儿配方奶粉能够促进婴儿脂肪消化并且改善脂质代谢过程。

关键词: 乳脂肪球膜;开发制备;脂肪球结构;婴儿脂肪消化;脂质代谢

Abstract: The milk fat globule membrane (MFGM) is a three-layer membrane structure that surrounds milk fat globules. The structure of fat globules in cow milk-based and soy-based infant formulas, lacking MFGM, is quite different from that in human milk. Therefore, addition of exogenous MFGM and preparation of infant formulas with fat globule structure similar to that in human milk have become the focus of recent research. In this article, we review the characteristics and development of MFGM, as well as the application of bovine MFGM in emulsions and infant formulas mimicking the human milk fat globule structure. Simulated in vitro infant gastrointestinal digestion and rodent studies in vivo have demonstrated that the mimic structure of human milk fat globule in emulsions and infant formulas can promote fat digestion and improve lipid metabolism in infants.

Key words: milk fat globule membrane; development and preparation; fat globule structure; fat digestion in infants; lipid metabolism

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