3D打印加工荷载绿原酸水凝胶体系的适印性和适用性

摘要/Abstract

摘要： 3D食品打印（3D Food Printing Process，3DFP）是一种符合未来生活方式的高效食品加工方式。水凝胶作为递送体系因具有显著特点，而成为研究的热点。本文旨在探究3DFP加工对荷载绿原酸（Chlorogenic acid，CA）甲基纤维素/透明质酸水凝胶体系结构、物性、功能、荷载CA效果等影响，揭示水凝胶在3DFP加工适印性和适用性规律。因此，本研究对荷载CA水凝胶体系进行3DFP，测定其质构特性、流变特性、微观结构、包埋率及消化特性。研究表明满足3DFP加工的最佳荷载CA水凝胶体系为水:甲基纤维素:透明质酸:CA=100:8:0.5:0.5。与其他配比及3DFP加工前相比，该体系经3DFP加工后的3D打印物，宽度偏差最小，为13.40%，硬度最高，弹性最大，且粘附性最小，结构紧密，孔隙均匀，不易塌陷，支撑性好，打印成型性最好。3DFP加工对水凝胶物理结构有良好的优化效果，而且不会改变水凝胶的化学性质；CA包埋率比3D打印前提高了22.09%；在胃肠消化模拟中，3DFP加工后样品CA释放率显著高于3DFP加工前样品CA释放率，具有良好缓释作用，其体外释放符合Ritger-Peppas方程模型。研究表明该水凝胶体系具有良好的适印性和适用性，3DFP加工对荷载CA水凝胶及其功能因子CA靶向释放有显著改善效果。

关键词: 3D食品打印加工, 水凝胶, 绿原酸, 适印性, 适用性, 递送体系

Abstract: 3D Food Printing (3DFP) is an efficient way of Food processing in line with the future lifestyle. As a delivery system, hydrogel has become a research hotspot because of its remarkable characteristics. The purpose of this paper is to explore the effects of 3DFP processing on the structure, physical properties, functions and loading CA effect of methylcellulose/hyaluronic acid hydrogels, and reveal the printability and applicability of hydrogels in 3DFP processing. Therefore, in this study, 3DFP was performed on loaded CA hydrogel system to measure its texture properties, rheological properties, microstructure, embedding rate and digestive properties. The results showed that the best loading CA hydrogel system for 3DFP processing was water: methyl cellulose: hyaluronic acid: CA=100:8:0.5:0.5. Compared with other ratios and pre-printing samples, 3DFP products of this system after 3DFP processing of the deviation was the smallest, which was 13.40%, and had the highest hardness, maximum elasticity, minimum adhesion, compact structure, uniform porosity, not easy to collapse, good support, and the best printing molding. 3DFP processing had a good optimization effect on the physical structure of hydrogel, and did not change the chemical properties of hydrogel; CA embedding rate was 22.09% higher than before 3D printing. In gastrointestinal digestion simulation, the CA release rate of 3DFP processed samples was significantly higher than that of 3DFP processed samples, showing a good sustained release effect, and its in vitro release was consistent with the Ritger-Peppas equation model. The results showed that the hydrogel system had good printability and applicability, and 3DFP processing can significantly improve the loaded CA hydrogel and its functional factor CA release.

Key words: 3D food printing processing, Hydrogel, Chlorogenic acid, Printability, Applicability, Delivery system

中图分类号:

TS218

南希骏周泉城嵇威厉佳怡王红磊倪乙丹李娅婕郭婷婷盛桂华. 3D打印加工荷载绿原酸水凝胶体系的适印性和适用性[J]. 食品科学, 0, (): 0-0.

Xi-Jun NAN Wei Ji Hong-Lei WANG Guihua Sheng. Printability and Applicability of 3D Printing System Loaded with Chlorogenic Acid Hydrogel[J]. FOOD SCIENCE, 0, (): 0-0.

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