食品科学 ›› 2024, Vol. 45 ›› Issue (18): 326-341.doi: 10.7506/spkx1002-6630-20231007-025

• 专题论述 • 上一篇    下一篇

海参皂苷结构特征及其生物活性和作用机制研究进展

刘煜珺, 郑 杰, 刘东竹, 于 笛, 李 龙, 傅志宇, 刘桂英, 周遵春   

  1. (1.辽宁省海洋水产科学研究院,辽宁 大连 116023;2.农业农村部水产种质资源保护与发掘利用重点实验室,辽宁 大连 116023;3.大连海洋大学食品科学与工程学院,辽宁 大连 116023)
  • 出版日期:2024-09-25 发布日期:2024-09-09
  • 基金资助:
    辽宁省应用基础研究计划项目(2022JH2/101300287);辽宁省农业科学院农业绿色高质量发展专项(2021HQ1917); 大连市揭榜挂帅技术攻关项目(2023JB11SN008);辽宁省农科院院长基金项目(2022QN2322)

Research Progress in Structural Characteristics, Biological Activity and Mechanism of Action of Sea Cucumber Saponins

LIU Yujun, ZHENG Jie, LIU Dongzhu, YU Di, LI Long, FU Zhiyu, LIU Guiying, ZHOU Zunchun   

  1. (1. Liaoning Ocean and Fisheries Science Research Institute, Dalian 116023, China; 2. Key Laboratory of Protection and Utilization of Aquatic Germplasm Resource, Ministry of Agriculture and Rural Affairs, Dalian 116023, China; 3. College of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China)
  • Online:2024-09-25 Published:2024-09-09

摘要: 海参皂苷是海参的主要次生代谢产物,是其进行化学防御的物质基础,具有抗肿瘤、提高免疫力和改善代谢综合征等多种生物活性,在保健品和药物开发领域具有广阔的应用前景。海参皂苷种类复杂多样,结构特征对其生物活性影响很大。本文在总结海参皂苷生源种类的基础上,重点对其结构特征以及生物活性和作用机制的研究现状进行系统归纳和总结,并对其未来的发展前景进行展望,以期为海参皂苷的进一步高值化开发利用提供参考。

关键词: 海参皂苷;结构特征;生物活性;作用机制

Abstract: Saponins are the primary secondary metabolites of sea cucumber, which are the material basis for its chemical defense. Sea cucumber saponins possess multiple biological properties including antitumor activity, immunoenhancing effect and ameliorative effect on metabolic syndrome, and therefore hold great promise in the development of health products and drugs. Sea cucumber saponins are complex and diverse, and their structural characteristics greatly affect their biological activities. This review begins with an overview of the sources and types of sea cucumber saponins, and then focuses on systematically summarizing the current status of research on their structural characteristics, bioactivities and action mechanisms. Finally, it gives an outlook on future prospects. We expect this review will provide a reference for the high-value development and utilization of sea cucumber saponins.

Key words: sea cucumber saponins; structural characteristics; biological activity; mechanism

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