食品科学 ›› 2025, Vol. 46 ›› Issue (18): 317-286.doi: 10.7506/spkx1002-6630-20250310-072

• 专题论述 • 上一篇    下一篇

微流控技术在食品研究中的应用

谢嘉俊,杨东,林建涵,赵靓,廖小军   

  1. (1.中国农业大学食品科学与营养工程学院,国家果蔬加工工程技术研究中心,农业农村部果蔬加工重点实验室,食品非热加工北京市重点实验室,北京 100083;2.中国农业大学信息与电气工程学院,农业农村部农业信息获取技术重点实验室,北京 100083)
  • 出版日期:2025-09-25 发布日期:2025-08-19
  • 基金资助:
    国家自然科学基金优秀青年科学基金项目(3232206);“十四五”国家重点研发计划重点专项(2024YFD2101400); 财政部和农业农村部:国家现代农业产业技术体系资助项目(CARS-24-E-03); 中国农业大学2115人才工程资助项目

Recent Advances in the Application of Microfluidic Technology in Food Science

XIE Jiajun, YANG Dong, LIN Jianhan, ZHAO Liang, LIAO Xiaojun   

  1. (1. National Engineering Research Center for Fruits and Vegetables Processing, Key Laboratory of Fruit and Vegetable Processing, Ministry of Agriculture and Rural Affairs, Beijing Key Laboratory for Food Non-thermal Processing, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China;2. Key Laboratory of Agricultural Information Acquisition Technology, Ministry of Agriculture and Rural Affairs, College of Information and Electrical Engineering, China Agricultural University, Beijing 100083, China)
  • Online:2025-09-25 Published:2025-08-19

摘要: 微流控技术作为一种新兴的多学科交叉技术,凭借其在微通道中精确控制流体的能力,在食品研究中展现出巨大的应用潜力。与传统方法相比,微流控技术具有更高通量、更快检测速度、更低成本和更加便携等优势,尤其在食源性病原体、农兽药残留、过敏原检测和乳液制备等方面表现突出。微流控技术主要包括连续流微流控(continuous flow microfluidics,CMF)技术、液滴微流控(droplet microfluidics,DMF)技术以及纺丝微流控技术,其中CMF和DMF应用最为广泛。本文综述了CMF在食品安全检测、成分鉴定、智能包装和DMF在酶与菌株定向筛选、乳液制备及包封递送等方面的最新进展。目前,尽管部分技术仍处于实验室阶段,但随着技术的不断发展和多学科交叉研究的深入,微流控技术有望在食品安全、质量控制和营养增强等方面提供更高效、精确的解决方案,推动食品行业的革新。

关键词: 连续流微流控;液滴微流控;食品安全;定向筛选;应用

Abstract: Microfluidics, an emerging interdisciplinary technology, shows great potential in food research due to its precise fluid control in microchannels. Compared with conventional methods, it offers advantages such as higher throughput, faster speed, cheaper cost, and more convenient, and outperforms in detecting foodborne pathogens, pesticide/veterinary residues and allergens and in preparing emulsions. Microfluidic technology mainly includes continuous flow microfluidics (CMF), droplet microfluidics (DMF), and spinning microfluidics (SMF), among which CMF and DMF are applied most extensively. This article summarizes the latest advances in the application of CMF for food safety testing, composition analysis and smart packaging, and the application of DMF for targeted enzyme/strain screening and emulsion preparation for the encapsulation and delivery of bioactives. While some technologies are still in the laboratory stage, ongoing interdisciplinary innovations will enhance food safety, quality control and nutrition, thus driving transformative solutions for the food industry.

Key words: continuous flow microfluidics; droplet microfluidics; food safety; targeted screening; application

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