FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (23 ): 419-421.doi: 10.7506/spkx1002-6300-200923094

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Immunoregulation Functions of Pupa Polypeptides in Mice

QI Ying-xin1,MENG Jun2,CAO Bai-ying1,FEI Bao-liang1,WEN Qi-long1   

  1. 1. College of Food Engineering, Jilin Teachers’Institute of Engineering and Technology, Changchun 130052, China;
    2. Institute for Food and Drug Control of Tonghua City of Jilin Province, Tonghua 134000, China
  • Received:2009-08-24 Online:2009-12-01 Published:2010-12-29
  • Contact: QI Ying-xin E-mail:qyxlclhb@163.com

Abstract:

In order to investigate immunoregulation functions of pupa polypeptides, mice were randomly divided 3 groups and conducted to oral administration of pupa polypeptides at the doses of 5.0, 1.7 g/kg·d and 0.6 g/kg·d for 40 days, respectively. Changes in immune organ index, delayed-type hypersensitivity (DTH), number of antibody-producing cells and carbon clearance capability were examined to evaluate immune functions. Results indicated that pupa polypeptides could significantly improve thymus index, promote plantar swelling, increase the generation of antibody-producing cells and enhance capability of monocyte-macrophage phagocytosis. Therefore, pupa polypeptides exhibited a significant effect on improvement of immune functions in mice.

Key words: pupa protein, polypeptide, immunoregulation effect

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