FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (23 ): 432-435.doi: 10.7506/spkx1002-6300-200923097

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Total Antioxidant Capacity and Protective Effect of Extract from Hairy Roots of Glycyrrhiza uralensis Fisch on CCl4-induced Acute Liver Injury in Mice

XIE Li-qiong1,LI Hai-fang2,Deliluer2   

  1. 1. College of Life Science and Technology, Xinjiang University, Urumqi 830046, China;
    2. Xinjiang Institute for Drug Control, Urumqi 830001, China
  • Received:2009-04-27 Online:2009-12-01 Published:2010-12-29
  • Contact: XIE Li-qiong E-mail:xieliqiong@gmail.com

Abstract:

Total antioxidant capacity and protective effect of extract from hairy roots of Glycyrrhiza uralensis Fisch (EHRG) on CCl4-induced acute liver injury in mice were evaluated, using extract from decoction pieces of G.uralensis F (EDPG) as positive control. Results showed that SOD, MDA and T-AOC level in EHRG-treated were significantly better than those in the model group, and similar to those in positive control group. EHRG treatment exhibited little effect on AST, ALT level, while EDPG did. EHRG reduced the LDH level, as the EDPG did, compared to the model group. Pathological section showed that both EHRG and EDPG exhibited protective effect on the injury of live.

Key words: Glycyrrhiza uralensis Fisch, hairy roots of Glycyrrhiza uralensis Fisch, carbon tetrachloride-induced acute liver injury, antioxidant capacity

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