Primary Study on Anti-tumor Components in Broccoli and Their Bioactivity

doi:10.7506/spkx1002-6630-200907056

Abstract

Abstract:

Objective: Broccoli is one of the green vegetables with high nutrition. This study was designed to isolate and analyze the anti-tumor promoters in broccoli. Method: Compounds A and B were isolated from the fresh flower buds of broccoli via the extractions of methanol, EtOAc and n-BuOH and the purifications of silica gel column, thin layer chromatography and high performance liquid chromatography in turn. Then the structures of two compounds were identified by spectroscopic data of NMR and FAB-MS, and the anti-tumor-promoting activity was examined by an immunoblotting analysis. Results: Compounds A, B are identified as monolinolenoylglycerol and monolinoleoylglycerol, respectively, which may inhibit the induction of EBV EA in the early stage at respective concentrations of 140 mol/L and 150 mol/L in the medium. Conclusion: There are anti-tumor promoters in green vegetables, and cancer may be prevented by intake of vegetables.

Key words: broccoli, anti-tumor, bioactive component

CLC Number:

R151

WANG Rong HE Lei. Primary Study on Anti-tumor Components in Broccoli and Their Bioactivity[J]. FOOD SCIENCE, 2009, 30(7 ): 243-245.

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Primary Study on Anti-tumor Components in Broccoli and Their Bioactivity

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