Study on Antistress Properties of Rhodiola Capsule in Mice

doi:10.7506/spkx1002-6630-200911054

FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (11): 240-242.doi: 10.7506/spkx1002-6630-200911054

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Study on Antistress Properties of Rhodiola Capsule in Mice

YANG Xiao-yan1,2，LOU Deng-ji1,2，LU Qi-qin1,2，SHEN Jian-wei1,2，WANG Huan1,2，ZHANG Xiao-feng1,*

(1.Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xi’ning 810008, China；
2.Graduate University of Chinese Academy of Sciences, Beijing 100049, China)

Received:2008-10-14 Revised:2009-01-10 Online:2009-06-01 Published:2010-12-29
Contact: ZHANG Xiao-feng1,* E-mail:yxyzhc@126.com

Abstract

Abstract:

The antistress properties of Rhodiola capsule were investigated in Kunming mice exposed to various experimental models of stress. Mice were randomly divided into a control group without administration of Rhodiola solution and two experimental groups once a day administered with Rhodiola solution at the dose of 1.0 g/kg bw and 0.5 g/kg bw by ig route for 30 days. The normobaric hypoxia, cold and heat endurance, hemoglobin (Hb) content of blood and survival time after ip NaNO2 administration were measured. Rhodiola treatments at both the doses were able to provide good protection against stress induced by hypoxia and high or low temperature when compared to the untreated mice. The normobaric hypoxia, cold and heat endurance time, survival time after NaNO2 poisoning were significantly extended and the Hb conctent was markedly higher than that of the control mice.

Key words: Rhodiola capsule, normobaric hypoxia, NaNO2, Hb, high temperature, low temperature

CLC Number:

Q946.91

YANG Xiao-yan1,2，LOU Deng-ji1,2，LU Qi-qin1,2，SHEN Jian-wei1,2，WANG Huan1,2，ZHANG Xiao-feng1,*. Study on Antistress Properties of Rhodiola Capsule in Mice[J]. FOOD SCIENCE, 2009, 30(11): 240-242.

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Study on Antistress Properties of Rhodiola Capsule in Mice

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