FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (17): 64-67.doi: 10.7506/spkx1002-6630-201017015

• Basic Research • Previous Articles     Next Articles

in vitro Inhibitory Effect of Water Extract from Douchi on Alpha-glucosidase Activity

CHEN Jing1,LI Li-te2   

  1. 1. Logistics School, Beijing Wuzi University, Beijing 101149, China;
    2. College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China
  • Received:2010-01-08 Online:2010-09-15 Published:2010-12-29
  • Contact: CHEN Jing E-mail:chenjingsusan@126.com

Abstract:

Thirty-seven Douchi samples collected from various regions of China were tested for the inhibitory effects of their water extracts on alpha-glucosidase in vitro. The water extracts from all these Douchi samples could inhibit mouse intestinal alpha-glucosidase to a certainty extent. In addition, samples NO.5 (L.Y), NO.16 (W.N.H) and NO.21 (M.W) showed stronger inhibitory effect against the enzyme (P < 0.05). Moreover, microamounts of glucose existing in Douchi samples had less interrupting effect on the anti-hyperglycemic activity of Douchi water extract. This study suggests that there are some active components in Douchi, which can strongly inhibit alpha-glucosidase and present excellent water solubility. These components may have sacchride-like structures. However, this needs to be deeply investigated.

Key words: Douchi, water extract, alpha-glucosidase, active components

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