Alpha-glucosidase Inhibiting Effect of DPPH free Radical Scavenging Activity of Flavonoid-rich Extract from Leaves of Crataegus cuneata Sieb. et Zucc

doi:10.7506/spkx1002-6630-201019038

FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (19): 179-181.doi: 10.7506/spkx1002-6630-201019038

• Basic Research • Previous Articles Next Articles

Alpha-glucosidase Inhibiting Effect of DPPH free Radical Scavenging Activity of Flavonoid-rich Extract from Leaves of Crataegus cuneata Sieb. et Zucc

DONG Hua-qiang1，ZHEN Chang-di1，ZHANG Yi2，LI Mei1，LIU Fu-lai1，HUANG Jian-bo1

1. Department of Food Science, Foshan University, Foshan 528231, China；2. College of Light Industry and Food Sciences,
South China University of Technology, Guangzhou 510641, China

Received:2010-07-06 Revised:2010-09-29 Online:2010-10-15 Published:2010-12-29
Contact: DONG Hua-qiang E-mail:huaqiangdong@163.com

Abstract

Abstract:

A flavonoid-rich extract obtained by ethyl acetate extraction from the 80% ethanol extract from the leaves of Crataegus cuneata Sieb. et Zucc was evaluated for its alpha-glucosidase inhibiting effect and DPPH free radical scavenging activity. The extract had an inhibitory effect on alpha-glucosidase derived from yeast, and the maximum inhibitory rate was up to 64.3%, and the inhibition was uncompetitive according to the Lineweaver-Burk plot. The maximum DPPH free radical scavenging rate of the extract was up to 52.8%, and the IC50 was 0.57 mg/mL. In conclusion, the extract had strong ability to inhibit yeast-derived alphaglucosidase and certain antioxidant activity.

Key words: leaves Crataegus cuneata Sieb. et Zucc, flavonoids, alpha-glucosidase, inhibiting effect, antioxidation

CLC Number:

TS201.2

DONG Hua-qiang1，ZHEN Chang-di1，ZHANG Yi2，LI Mei1，LIU Fu-lai1，HUANG Jian-bo1. Alpha-glucosidase Inhibiting Effect of DPPH free Radical Scavenging Activity of Flavonoid-rich Extract from Leaves of Crataegus cuneata Sieb. et Zucc[J]. FOOD SCIENCE, 2010, 31(19): 179-181.

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Alpha-glucosidase Inhibiting Effect of DPPH free Radical Scavenging Activity of Flavonoid-rich Extract from Leaves of Crataegus cuneata Sieb. et Zucc

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