FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (3 ): 152-155.doi: 10.7506/spkx1002-6630-201103036

• Bioengineering • Previous Articles     Next Articles

Anti-Aspergillus niger Activity of Metal/Chitosan Complexes

FENG Xiao-qiang,LI Xiao-fang,YANG Sheng,FU Guo-qing,WANG Ting-pu   

  1. 1. College of Life Science and Chemistry, Tianshui Normal University, Tianshui 741001, China;2. Department of Chemistry,
    Dingxi Teachers College, Dingxi 743000, China;3. Traditional Medical Hospital of Tianshui, Tianshui 741001, China
  • Received:2010-05-07 Revised:2010-12-22 Online:2011-02-15 Published:2011-01-13
  • Contact: FENG Xiao-Qiang E-mail:fengxiaoq04@lzu.cn

Abstract: Chitosan and metal/chitosan complex were evaluated comparatively for their anti-Aspergillus niger activity based on the mycelial growth and spore germination of the fungus. The results showed that both chitosan and metal-chitosan could effectively inhibit the mycelial growth of A. niger and its spore germination, while chitosan displayed lower antifungal activity than its complexes with Zn or Ni, and chitosan/ Ni complex showed the strongest antifungal activity. This biological activity of chitosan was largely influence by its molecular weight and concentration as well as environmental pH. The complex between chitosan with 5 kD molecular weight and Ni had the best inhibitory effect on A. niger. The inhibitory effect of chitosan/Ni complex revealed a change trend opposite to that of pH ranging from 3 to 7.5, but increased with increasing concentration from 0 to 0.75 mg/mL.

Key words: metal/chitosan complex, Aspergillus niger, antifungal activity

CLC Number: