FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (15): 251-254.doi: 10.7506/spkx1002-6630-201115055

• Nutrition & Hygiene • Previous Articles     Next Articles

Protective Effect of Acid-insoluble Protein from Millet against CCl4-induced Liver Injury in Mice

XU Jie,WANG Chang-qing*,ZHAO Chen-yong,FAN Ying,WANG Fei   

  1. (College of Life Science, Shanxi University, Taiyuan 030006, China)
  • Received:2018-04-20 Revised:2018-04-20 Online:2011-08-15 Published:2011-07-26

Abstract: In this paper, the protective effect of acid-insoluble protein from millet against CCl4-induced liver injury in mice was explored. The results indicated that serum ALT and AST levels and hepatic MDA content in mice treated with acid-insoluble protein from millet were significantly lower than those in mice from the liver damage model group (P <0.05). Meanwhile, abnormal morphology of mouse liver surface, necrosis of liver cells, steatosis and inflammatory cells infiltration were reduced by dietary administration with acid-insoluble protein from millet in a dose-dependent manner. Therefore, millet acid insoluble protein can protect mice from acute liver injury induced by CCl4.

Key words: millet, acid-insoluble protein, CCl4-induced liver injury, protective capability

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