FOOD SCIENCE ›› 2013, Vol. 34 ›› Issue (7): 196-200.doi: 10.7506/spkx1002-6630-201307041

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Screening of Fungal Elicitor for Fermentative Production of Natamycin and Optimization of Induction Conditions

WEI Bao-dong ,PAN Ya-hui,WANG Ya-nan,WANG Li-yan   

  1. College of Food Science, Shenyang Agricultural University, Shenyang 110866, China
  • Received:2012-05-10 Revised:2013-02-24 Online:2013-04-15 Published:2013-03-20
  • Contact: WEI Bao-dong E-mail:bdwei2003@yahoo.com.cn

Abstract: Preliminary screening was carried out to obtain fungal elicitor that induces natamycin production by Streptomyces chattanovgensis. The optimal induction conditions were established by mathematical modelling mathematical modelling based on Box-Behnken experimental design and response surface analysis. The potent inducing effect of the fungal elicitors on natamycin production was confirmed. When fungal elicitor from Aspergillus niger was added to a final concentration of 122 μg/mL after 18.3 h natamycin fermentation and incubated for 78.5 h, the observed average yield of natamycin in fermentation broth was 2.89 g/L, 1.68 times higher than the blank control.

Key words: fungal elicitor, fermentation, natamycin, response surface analysis

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