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Preparation and Physico-chemical Characterization of EGCG-phospholipid Complex

LEI Shi-cheng,HU Bing,SUN Yi*,ZHANG Xin,ZENG Xiao-xiong   

  1. College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
  • Online:2013-07-15 Published:2013-06-28
  • Contact: SUN Yi

Abstract:

In this study, EGCG-phospholipid complex was prepared through the dissolution of EGCG and soybean
lecithin in ethanol, and its structure was characterized by UV spectroscopy, IR spectroscopy, X-ray powder diffractometry
and differential scanning calorimetry. Meanwhile, the apparent water/n-octanol partition coefficient of this complex was
determined. The results showed that non-covalent bonding between EGCG and phospholipid under experimental conditions
generated the target complex. Furthermore, the solubility of EGCG was improved according to apparent partition coefficients
of EGCG and EGCG-phospholipid complex in n-octanol buffer solution system.

Key words: EGCG, EGCG-phospholipid complex, spectral analysis, X-ray power diffractometry (X-RPD), differential scanning calorimetry (DSC)

CLC Number: