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Anti-alcoholism Effects of Corn Protein Hydrolysate

MA Yanqiu1,2, ZHENG Xiqun1,2,*, LIU Xiaolan1,2, SUN Qi1   

  1. 1. College of Food and Biological Engineering, Qiqihar University, Qiqihar 161006, China; 2. Key Constructive Laboratory of
    Processing Agricultural Products of Heilongjiang Province Normal University, Qiqihar University, Qiqihar 161006, China
  • Online:2015-01-15 Published:2015-01-16

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Abstract:

The enzymatic hydrolysate of extruded corn gluten produced by sequential hydrolysis with Alcalase and Protamex
was evaluated for its anti-alcoholism effect in mice. The results showed that the hydrolysate contained 87.76% peptides which
molecular weight is less than 1 000 u, and was richer in glutamic acid, leucine and alanine than corn gluten. Gavage administration of
the enzymatic hydrolysate resulted in a 59.43% reduction in blood alcohol concentrations in mice when compared with the model group.
Moreover, this hydrolysate increased alcohol dehydrogenase (ADH) activity in the stomach of mice, and enhanced superoxide dismutase
(SOD) activity and glutataione (GSH) content but reduced malondialdehyde (MDA) content in the liver within a certain time range.

Key words: corn protein hydrolysate, anti-alcoholism effects, sequential two-enzyme hydrolysis

CLC Number: