Abstract:

Protein plays an important role in human metabolism, immunity and disease occurrence. At present, proteins
have been studied in the fields of biology, medicine, food and others. The technologies used for protein research have
become the focus of worldwide attention. Developing functional fluorescent nano-materials with good optical properties and
biocompatibility is of great significance for the labeling, analysis and separation of protein. In this paper, the basic properties
of fluorescent nano-materials are outlined, such as semiconductor quantum dots, embedded core-shell nanoparticles, carbon
dots, carbon nanotubes, precious metal element nano-clusters, and fluorescent magnetic nanoparticles. We also review the
applications of these kinds of nano-materials in protein marker imaging, protein interaction, protein immobilization and
separation, and protein detection.

Key words: fluorescence, nanometer materials, protein, application